Browse our latest Chromosomes and Gene Expression articles

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    1. Chromosomes and Gene Expression

    Cell-cycle-resolved Hi-C reveals unexpected plasticity of A/B compartments across interphase

    Linda Choubani, Hisashi Miura ... Ichiro Hiratani
    Nuclear A/B compartments are dramatically remodeled by S‑phase entry and weaken in G2, revising the model of cell‑cycle chromatin dynamics and placing G1/S as a key transition.
    1. Chromosomes and Gene Expression

    Dual regulation of chemical stress-induced DDI2/3 expression by a transcription factor Fzf1 and nucleosome in Saccharomyces cerevisiae

    Ying Du, Aiyang Lin ... Wei Xiao
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression

    Shared binding sites for the chromosomal architectural protein Su(Hw) mediate physical interactions between Drosophila TAD boundaries

    Wenfan Ke, Miki Fujioka ... Paul Schedl
    Not revised
    Reviewed Preprint v1
    • Useful
    • Convincing
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA

    Zhuo Bi, Yu-Xiang Chen ... Babak Javid
    The ribosomal rRNA methyltransferase GidB is involved in the discrimination of mischarged tRNAs in mycobacteria.
    1. Chromosomes and Gene Expression

    Volatile diacetyl triggers rapid fmo-2 expression through DHAP-glycerol shunt induction

    Marco Giorda, Anamitra Sen, Martin S Denzel
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Cell Biology
    2. Chromosomes and Gene Expression

    A genetic toolkit for stable transgenesis in the anaerobic gut parasite Blastocystis ST7-B

    M Rey Toleco, Kevin SW Tan, Mark van der Giezen
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Nucleation-dependent propagation of Polycomb modifications emerges during the Drosophila maternal to zygotic transition

    Natalie Gonzaga-Saavedra, Eleanor A Degen ... Shelby A Blythe
    Epigenomics and quantitative imaging are used to investigate the re-establishment of histone modifications associated with the Polycomb group of epigenetic regulators during the Drosophila maternal-to-zygotic transition.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Explainable machine learning-assisted exploration of chromatin dynamics reveals chromosome-specific response to serum starvation

    Taras Redchuk, Antti P Pennanen ... Maria K Vartiainen
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Chromosomes and Gene Expression
    2. Physiology

    Gene dosage imbalance disrupts systemic metabolism in the Dp16 Down syndrome mouse model

    Fangluo Chen, Muzna Saqib ... G William Wong
    Gene dosage imbalance due to the triplication of human chromosome 21 gene orthologs impairs whole-body glucose and lipid metabolism by disrupting homeostatic processes across major metabolic tissues.
    1. Chromosomes and Gene Expression
    2. Physics of Living Systems

    Cluster size determines internal structure of transcription factories in human cells

    Massimiliano Semeraro, Giuseppe Negro ... Davide Marenduzzo
    In a polymer model of chromatin that explicitly incorporates different types of transcription factors, both specialised and mixed factories emerge naturally, with their composition governed by their size.
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