Browse our latest Chromosomes and Gene Expression articles

Bidirectional regulation of the chromatin modification H3K27me3 orchestrates programs of gene expression that underlie postmitotic stages of neuronal maturation.

TATA-box binding protein is not required for RNA Polymerase II transcription in mouse embryonic stem cells.

Single-cell chromatin accessibility analysis reveals the intricate regulatory landscape of mouse testicular development, uncovering novel cell subpopulations and transcription factors, and offering valuable insights into the molecular mechanisms driving germ cell and somatic cell maturation.

RNA polymerase II transcription can efficiently occur when mouse embryonic stem cells lack TBP and TBP-like proteins, confirming that this initiation factor may not be as essential as once thought.

Regulatory hierarchies controlling sex determination and X-chromosome dosage compensation between closely-related nematode species are conserved, but X-chromosome target specificity for the condensin dosage compensation complex has diverged, thereby contributing to reproductive isolation.

CBFs, the central regulators of low-temperature signaling, have a function to directly activate the expression of COOLAIR, an antisense RNA of FLC, during vernalization process, but COOLAIR is not required for the vernalization response.

A well-established model for how plants start the process of flowering in periods of cold weather may need revisiting.

The lncRNA pCharme controls the expression of cardiomyocyte maturation genes and heart development by orchestrating the formation of MATR3-enriched nuclear condensates.

eRNAs detected in patient-derived transcriptomic data can delineate potential active enhancer regions in oesophageal adenocarcinoma and uncover genes associated with the cancer phenotype.

Genetic and cytological analyses reveal a regulatory circuit that controls a key cell cycle transition during meiosis and mediates feedback regulation in response to meiotic defects.