Browse our latest Chromosomes and Gene Expression articles

Page 21 of 119
    1. Chromosomes and Gene Expression
    2. Plant Biology

    Flowering: Keeping it cool

    Vy Nguyen, Iain Searle
    A well-established model for how plants start the process of flowering in periods of cold weather may need revisiting.
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    Insight
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart

    Valeria Taliani, Giulia Buonaiuto ... Monica Ballarino
    The lncRNA pCharme controls the expression of cardiomyocyte maturation genes and heart development by orchestrating the formation of MATR3-enriched nuclear condensates.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    eRNA profiling uncovers the enhancer landscape of oesophageal adenocarcinoma and reveals new deregulated pathways

    Ibrahim Ahmed, Shen-Hsi Yang ... Andrew D Sharrocks
    eRNAs detected in patient-derived transcriptomic data can delineate potential active enhancer regions in oesophageal adenocarcinoma and uncover genes associated with the cancer phenotype.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Recruitment of Polo-like kinase couples synapsis to meiotic progression via inactivation of CHK-2

    Liangyu Zhang, Weston T Stauffer ... Abby F Dernburg
    Genetic and cytological analyses reveal a regulatory circuit that controls a key cell cycle transition during meiosis and mediates feedback regulation in response to meiotic defects.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    A transcriptome atlas of leg muscles from healthy human volunteers reveals molecular and cellular signatures associated with muscle location

    Tooba Abbassi-Daloii, Salma el Abdellaoui ... Vered Raz
    Molecular atlas of Human leg muscles molecular atlas reveals muscle-specific signatures that discriminate between muscle groups.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress

    Adwait A Godbole, Sneha Gopalan ... Amy K Walker
    Histone methylation patterns may differ depending on the enzymatic source of the methyl donor S-adenosylmethionine, suggesting the biological effects of low SAM may affect methylation targets in different ways, depending on the synthase producing it.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Synthetic analysis of chromatin tracing and live-cell imaging indicates pervasive spatial coupling between genes

    Christopher H Bohrer, Daniel R Larson
    The physical distance between genes in individual cells is the major factor driving co-transcriptional bursts, showing a significant degree of correlation for distances below 400 nm.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    RNA localization mechanisms transcend cell morphology

    Raeann Goering, Ankita Arora ... J Matthew Taliaferro
    Mechanisms that regulate RNA localization in one cell type predictably regulate RNA localization in other cell types, even if they have vastly different morphologies, implying an underlying regulatory code that cuts across specific subcellular structures.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Emergent dynamics of adult stem cell lineages from single nucleus and single cell RNA-Seq of Drosophila testes

    Amelie A Raz, Gabriela S Vida ... Margaret T Fuller
    Single nucleus and single cell RNA-seq data uncover novel transcriptomic perspectives in Drosophila testis biology and provide access to user-friendly tools for further scientific discovery in the field.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    An atrial fibrillation-associated regulatory region modulates cardiac Tbx5 levels and arrhythmia susceptibility

    Fernanda M Bosada, Karel van Duijvenboden ... Vincent M Christoffels
    Modest changes in expression of interacting dose-dependent transcription factors Tbx5 and Prrx1, caused by disease-associated common regulatory variants, significantly impact on the cardiac gene regulatory network and disease susceptibility.