Browse our latest Chromosomes and Gene Expression articles

Page 56 of 122
    1. Chromosomes and Gene Expression

    Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression

    Stefan Meinke, Gesine Goldammer ... Florian Heyd
    Competition between minor and major splice sites in SRSF10 controls cell type-dependent expression of all SR-proteins and reveals a global impact of the minor spliceosome on major intron splicing.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Drosophila SWR1 and NuA4 complexes are defined by DOMINO isoforms

    Alessandro Scacchetti, Tamas Schauer ... Peter B Becker
    Alternative splicing of a single gene generates functional diversity amongst chromatin regulators.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    An advanced cell cycle tag toolbox reveals principles underlying temporal control of structure-selective nucleases

    Julia Bittmann, Rokas Grigaitis ... Boris Pfander
    The development of an advanced cell cycle tag toolbox will enable a wide variety of cell cycle studies and shows post-replicative function of nucleases resolving replication/recombination structures.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Hfq CLASH uncovers sRNA-target interaction networks linked to nutrient availability adaptation

    Ira Alexandra Iosub, Robert Willem van Nues ... Sander Granneman
    High-throughput RNA-RNA interaction analysis uncovers many novel sRNA-target interactions at various growth stages in Escherichia coli.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Controlling gene activation by enhancers through a drug-inducible topological insulator

    Taro Tsujimura, Osamu Takase ... Keiichi Hishikawa
    A novel synthetic DNA cassette of CTCF-binding sites combined with the drug-controllable induction system of heterochromatin enabled switchable blocking of chromatin conformation and gene-enhancer interaction.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    An H3K9 methylation-dependent protein interaction regulates the non-enzymatic functions of a putative histone demethylase

    Gulzhan Raiymbek, Sojin An ... Kaushik Ragunathan
    A putative histone demethylase in fission yeast has non-enzymatic properties that regulates heterochromatin assembly and epigenetic inheritance.
    1. Chromosomes and Gene Expression

    Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment

    Mélanie Criqui, Aditi Qamra ... Lea Harrington
    Cell lineage tracing and biochemical analysis of cell fate during murine stem cell differentiation demonstrates a specific cooperativity between perturbations in histone methylation and eroded telomeres that destabilize cell differentiation.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    The histone deacetylase complex MiDAC regulates a neurodevelopmental gene expression program to control neurite outgrowth

    Baisakhi Mondal, Hongjian Jin ... Hans-Martin Herz
    Identification of the underlying molecular gene-regulatory mechanisms by which the histone deacetylase complex MiDAC controls neurite outgrowth.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Zygotic pioneer factor activity of Odd-paired/Zic is necessary for late function of the Drosophila segmentation network

    Isabella V Soluri, Lauren M Zumerling ... Shelby A Blythe
    Mechanisms for shaping the chromatin accessibility landscape operate during development to regulate how embryonic patterning information is interpreted at the level of gene regulatory networks.
    1. Chromosomes and Gene Expression

    Centromere deletion in Cryptococcus deuterogattii leads to neocentromere formation and chromosome fusions

    Klaas Schotanus, Joseph Heitman
    Centromere deletion in Cryptococcus deuterogattii results in neocentromeres, which span actively expressed genes and at elevated temperatures cen10∆ mutants are unstable leading to chromosome fusion and silencing of the neocentromere.