Browse our latest Computational and Systems Biology articles

Single-cell RNA sequencing analysis of diabetic mouse cavernous tissue revealed that LBH is a novel pericyte marker and may interact with Crystallin Alpha B and Vimentin to promote neurovascular regeneration.

Advanced statistical and computational methods are reviewed and compared for integrating microbiome, host genomics, and metabolomics data, together with future research directions.

Phantasus democratizes gene expression analysis, offering intuitive and interactive tools that streamline the exploration and analysis of user-provided data and over 96,000 public datasets.

A computational model of skeletal muscle regeneration reveals complex interplay of cytokines, angiogenesis, and cell behaviors, predicting that synergistic cytokine perturbations enhance skeletal muscle regeneration beyond individual cytokine interventions.

Three theoretical principles explain the neural activity observed in the head direction circuit of insects, the connectivity pattern underlying the circuit, and how the ubiquitous eight-column circuit structure emerged from evolutionary processes.

Those quoted and mentioned in stories in Nature News mostly have names associated with men and are much less likely to have names associated with East Asia.

Estimating cell type composition from a gene expression mixture remains a challenging task, as evidenced by how a simple regression model outperforms many state-of-the-art spatial deconvolution methods.