Browse our latest Computational and Systems Biology articles

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    1. Computational and Systems Biology

    MGPfactXMBD: A Model-Based Factorization Method for scRNA Data Unveils Bifurcating Transcriptional Modules Underlying Cell Fate Determination

    Jun Ren, Ying Zhou ... Qiyuan Li
    Not revised
    Reviewed Preprint v1
    1. Computational and Systems Biology

    AI-driven Automated Discovery Tools Reveal Diverse Behavioral Competencies of Biological Networks

    Mayalen Etcheverry, Clément Moulin-Frier ... Michael Levin
    Revised
    Reviewed Preprint v3
    Updated
    1. Computational and Systems Biology

    Pseudo-grading of tumor subpopulations from single-cell transcriptomic data using Phenotype Algebra

    Namrata Bhattacharya, Anja Rockstroh ... Debarka Sengupta
    Not revised
    Reviewed Preprint v1
    1. Computational and Systems Biology
    2. Neuroscience

    Neural population dynamics underlying evidence accumulation in multiple rat brain regions

    Brian DePasquale, Carlos D Brody, Jonathan W Pillow
    1. Structural Biology and Molecular Biophysics
    2. Computational and Systems Biology

    Discovery of a Heparan-Sulfate Binding Domain in Monkeypox Virus H3 Protein as a New Anti-poxviral Drug Target

    Bin Zheng, Meimei Duan ... Peng Zheng
    Not revised
    Reviewed Preprint v1
    1. Computational and Systems Biology

    Pathway activation model for personalized prediction of drug synergy

    Quang Thinh Trac, Yue Huang ... Trung Nghia Vu
    Not revised
    Reviewed Preprint v1
    1. Computational and Systems Biology

    Alleviating cell-free DNA sequencing biases with optimal transport

    Antoine Passemiers, Tatjana Jatsenko ... Yves Moreau
    Not revised
    Reviewed Preprint v1
    1. Computational and Systems Biology

    Convergent evolution in silico reveals shape and dynamic principles of directed locomotion

    Renata B Biazzi, André Fujita, Daniel Y Takahashi
    Revised
    Reviewed Preprint v2
    Updated
    1. Computational and Systems Biology
    2. Cancer Biology

    Computational Engineering of a Therapeutic Antibody to Inhibit Multiple Mutants of HER2 Without Compromising Inhibition of the Canonical HER2

    Sapir Peled, Julia Guez-Haddad ... Yanay Ofran
    Revised
    Reviewed Preprint v2
    Updated
    1. Structural Biology and Molecular Biophysics
    2. Computational and Systems Biology

    Structural characterization and dynamics of AdhE ultrastructures from Clostridium thermocellum: A containment strategy for toxic intermediates

    Samantha J Ziegler, Brandon C Knott ... Yannick J Bomble
    Revised
    Reviewed Preprint v2
    Updated
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