Browse our latest Developmental Biology articles

Page 124 of 211
    1. Developmental Biology

    Electron transport chain biogenesis activated by a JNK-insulin-Myc relay primes mitochondrial inheritance in Drosophila

    Zong-Heng Wang, Yi Liu ... Hong Xu
    An insulin-Myc feed-forward loop triggered by transient JNK boosts transcription of genes essential for mitochondrial respiration and biogenesis during early oogenesis to support massive mtDNA replication and inheritance in Drosophila.
    1. Cell Biology
    2. Developmental Biology

    Mitochondrial fusion is required for spermatogonial differentiation and meiosis

    Grigor Varuzhanyan, Rebecca Rojansky ... David C Chan
    Mitochondrial fusion enables a metabolic transition during spermatogenesis.
    1. Developmental Biology

    ZP4 confers structural properties to the zona pellucida essential for embryo development

    Ismael Lamas-Toranzo, Noelia Fonseca Balvís ... Pablo Bermejo-Álvarez
    Zona pellucida requires ZP4 protein to efficiently protect the developing embryo during in vivo pre-implantation development.
    1. Developmental Biology
    2. Evolutionary Biology

    Extraocular, rod-like photoreceptors in a flatworm express xenopsin photopigment

    Kate A Rawlinson, Francois Lapraz ... Maximilian J Telford
    A new opsin receptor is light-sensitive and expressed in a unique type of photoreceptor in a flatworm that encloses over 400 sensory cilia within its cell membrane.
    1. Cell Biology
    2. Developmental Biology

    Matrix metalloproteinase 1 modulates invasive behavior of tracheal branches during entry into Drosophila flight muscles

    Julia Sauerwald, Wilko Backer ... Stefan Luschnig
    Tracheal-derived matrix metalloproteinase 1 activity sustains tracheal branch invasion into myotubes by modulating ECM properties and dynamic behavior of sprouting tip cells.
    1. Cancer Biology
    2. Developmental Biology

    Coopted temporal patterning governs cellular hierarchy, heterogeneity and metabolism in Drosophila neuroblast tumors

    Sara Genovese, Raphaël Clément ... Cédric Maurange
    About twenty temporal patterning genes are identified that drive an irreversible differentiation trajectory governing the heterogeneity and proliferative properties of cells in neural tumors with an early developmental origin.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    A distinct transition from cell growth to physiological homeostasis in the tendon

    Mor Grinstein, Heather L Dingwall ... Jenna Lauren Galloway
    Mitotic labeling defines a change in cell division kinetics from growth to homeostasis and identifies slowly cycling cells in the adult tendon.
    1. Developmental Biology

    N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration

    Elif Kon, Elisa Calvo-Jiménez ... Yves Jossin
    FGFRs regulate multipolar cortical neuron orientation and the morphological change into bipolar cells in vivo under the control of N-Cadherin and the extracellular matrix protein Reelin.
    1. Cell Biology
    2. Developmental Biology

    BMP7 functions predominantly as a heterodimer with BMP2 or BMP4 during mammalian embryogenesis

    Hyung-Seok Kim, Judith Neugebauer ... Jan L Christian
    Endogenous BMP2/7 and BMP4/7 heterodimers form in vivo, and are the predominant functional ligand in many, if not all, tissues of developing mouse embryos.
    1. Developmental Biology

    Taste bud formation depends on taste nerves

    Di Fan, Zoubida Chettouh ... Jean-François Brunet
    The sensory nerves that carry sensations from the taste buds to the brain induce the formation of the taste buds in the embryo.