A genetic tracing study demonstrates that neural progenitor lineage dominance may not be maintained in differentiated progeny, underscoring the critical need for region-specific markers to validate pluripotent stem cell–derived products.
Laura E Cook, Charles Y Feigin ... Irene Gallego Romero
While the genes involved in craniofacial development are highly conserved between the fat-tailed dunnart and mouse, their cis-regulatory elements show significant divergence and appear to reflect species-specific developmental processes.
Bruno Gideon Bergheim, Alison G Cole ... Suat Özbek
Integrated proteomic and single-cell transcriptomic analyses define the Nematostella vectensis matrisome and reveal conserved extracellular matrix functions driving life cycle transitions in this non-bilaterian model.
Mouse sperm are unable to bind the zebrafish chorion, yet a subset of hyperactivated sperm can enter and cross the micropyle, suggesting a conserved mechanism of gamete interaction across species.
Introducing premature visual experience by opening the closed eyelids early in ferrets caused many cells in the primary visual cortex to mature improperly.
The first follicle wave undergoes atresia to amplify androgen-producing theca cells, while previously unknown wave 1.5 follicles leave quiescence at 2 weeks and produce most of the earliest offspring.
