Browse our latest Developmental Biology articles

Page 17 of 215
    1. Developmental Biology
    2. Cancer Biology

    Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma

    James Purzner, Alexander S Brown ... Matthew P Scott
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology

    The autophagy protein ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy

    Pooja Popli, Arin K Oestreich ... Ramakrishna Kommagani
    Autophagy sustains oviduct homeostasis, modulates inflammation, and prevents excessive pyroptosis, ensuring efficient embryo transport and a well-balanced reproductive tract environment.
    1. Developmental Biology

    Spatial transcriptomics in the adult Drosophila brain and body

    Jasper Janssens, Pierre Mangeol ... Frank Schnorrer
    Spatial transcriptomics of adult Drosophila brain and body sections determined the spatial expression for 150 genes, which identified the locations of unknown neuronal cell types and transcriptional diversity within muscle.
    1. Cell Biology
    2. Developmental Biology

    Endosomal-lysosomal organellar assembly (ELYSA) structures coordinate lysosomal degradation systems through mammalian oocyte-to-embryo transition

    Yuhkoh Satouh, Takaki Tatebe ... Ken Sato
    Imaging and correlative light and electron microscopy analyses of endosomal-lysosomal organellar assembly in mammalian oocytes elucidated statistic alteration in their size, distribution, and correlation with endo-lysosomal maturation during oocyte-to-embryo transition.
    1. Developmental Biology

    Probing metazoan polyphosphate biology using Drosophila reveals novel and conserved polyP functions

    Sunayana Sarkar, Harsha Sharma ... Manish Jaiswal
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Dual role of FOXG1 in regulating gliogenesis in the developing neocortex via the FGF signalling pathway

    Mahima Bose, Ishita Talwar ... Shubha Tole
    Foxg1 regulates gliogenesis in the mouse neocortex by modulating FGF signalling and integrating intrinsic and extrinsic mechanisms to ensure a balanced production of neurons, astrocytes, and oligodendrocytes in the brain.
    1. Developmental Biology

    Receptor tyrosine kinases CAD96CA and FGFR1 function as the cell membrane receptors of insect juvenile hormone

    Yan-Xue Li, Xin-Le Kang ... Xiao-Fan Zhao
    The cell membrane receptors of juvenile hormone, CAD96CA and FGFR1, regulate the genomic effects of juvenile hormone by phosphorylating intracellular receptor.
    1. Developmental Biology

    A comparative analysis of planarian regeneration specificity reveals tissue polarity contributions of the axial cWnt signalling gradient

    James P Cleland, Hanh T.-K Vu ... Jochen C Rink
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis

    Joseph A Bisson, Miriam Gordillo ... Todd Evans
    Differentiation of human pluripotent stem cells mutant for one GATA6 gene can model developmental heart defects seen in some patients with congenital heart disease.
    1. Developmental Biology
    2. Genetics and Genomics

    Evaluating the transcriptional regulators of arterial gene expression via a catalogue of characterized arterial enhancers

    Svanhild Nornes, Susann Bruche ... Sarah De Val
    Identification and characterization of enhancers for eight key arterial genes reveal transcription factors associated with different aspects of endothelial gene expression specificity and provide a tool for a better understanding of arterial differentiation.