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    1. Cell Biology
    2. Developmental Biology

    Rudhira-mediated microtubule stability controls TGFβ signaling during mouse vascular development

    Divyesh Joshi, Preeti Jindal ... Maneesha S Inamdar
    The precise integration of endothelial TGFβ signaling and microtubule stability directs cardiovascular development.
    1. Developmental Biology

    Single nuclei RNA-sequencing of adult brain neurons derived from type 2 neuroblasts reveals transcriptional complexity in the insect central complex

    Derek G Epiney, Gonzalo Morales Chaya ... Chris Q Doe
    The central complex of the adult Drosophila brain, required for sensorimotor integration, is transcriptionally complex as detected by single-cell transcriptome analysis.
    1. Developmental Biology
    2. Genetics and Genomics

    The robust, high-throughput, and temporally regulated roxCre and loxCre reporting systems for genetic modifications in vivo

    Mengyang Shi, Jie Li ... Bin Zhou
    Revised
    Reviewed Preprint v3
    Updated
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    1. Cell Biology
    2. Developmental Biology

    Krüppel Regulates Cell Cycle Exit and Limits Adult Neurogenesis of Mushroom Body Neural Progenitors in Drosophila

    Dongni Shao Chen, Jin Man ... Yuu Kimata
    Not revised
    Reviewed Preprint v1
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    • Solid
    • Incomplete
    1. Developmental Biology
    2. Physics of Living Systems

    Spiral-eyes: A soft active matter model of in vivo corneal epithelial cell migration

    Kaja Kostanjevec, Rastko Sknepnek ... Silke Henkes
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in Drosophila melanogaster

    Geovana S Garcia, Murilo F Othonicar ... Marcos T Oliveira
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Cancer Biology
    2. Developmental Biology

    VGLL2 and TEAD1 fusion proteins identified in human sarcoma drive YAP/TAZ-independent tumorigenesis by engaging EP300

    Susu Guo, Xiaodi Hu ... Junhao Mao
    Characterization of recurrent fusion proteins in rhabdomyosarcoma identified a Hippo pathway-independent mechanism involving VGLL2 and TEAD1 driving oncogenic transformation.
    1. Cell Biology
    2. Developmental Biology

    Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development

    Qian Wang, Hongge Li ... Xin Zhang
    FGF signaling drives lens development by recruiting Grb2 through Shc1, Frs2, and Shp2 to regulate transcription and cytoskeletal arrangements.
    1. Developmental Biology
    2. Evolutionary Biology

    Differences in size and number of embryonic type II neuroblast lineages correlate with divergent timing of central complex development between beetle and fly

    Simon Rethemeier, Sonja Fritzsche ... Vera S Hunnekuhl
    Genetic labeling and molecular analyses characterize the dynamics of embryonic central complex-forming type II neuroblast lineages in Tribolium castaneum.
    1. Cell Biology
    2. Developmental Biology

    Cell Signaling: Not all dimers are equal

    Jeet H Patel, Mary C Mullins
    Disease-causing mutations in the signaling protein BMP4 impair its secretion, but only when it is made as a homodimer.
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