Browse our latest Developmental Biology articles

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    1. Developmental Biology

    Integrated transcriptomic analysis of human induced pluripotent stem cell-derived osteogenic differentiation reveals a regulatory role of KLF16

    Ying Ru, Meng Ma ... Meng Wu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology

    Comparative analysis of the syncytiotrophoblast in placenta tissue and trophoblast organoids using snRNA sequencing

    Madeline M Keenen, Liheng Yang ... Carolyn B Coyne
    Trophoblast organoids recapitulate syncytiotrophoblast nuclear heterogeneity and reveal environment-dependent gene regulation critical for placental hormone production and differentiation.
    1. Developmental Biology
    2. Neuroscience

    Commissureless acts as a substrate adapter in a conserved Nedd4 E3 ubiquitin ligase pathway to promote axon growth across the midline

    Kelly G Sullivan, Greg J Bashaw
    Commissureless works with the Nedd4 E3 ubiquitin ligase to transiently degrade the Robo1 receptor to allow commissural axons to cross the midline.
    Version of Record
    Research Article
    • Fundamental
    • Compelling
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Rudhira-mediated microtubule stability controls TGFβ signaling during mouse vascular development

    Divyesh Joshi, Preeti Jindal ... Maneesha S Inamdar
    The precise integration of endothelial TGFβ signaling and microtubule stability directs cardiovascular development.
    1. Developmental Biology

    Single nuclei RNA-sequencing of adult brain neurons derived from type 2 neuroblasts reveals transcriptional complexity in the insect central complex

    Derek G Epiney, Gonzalo Morales Chaya ... Chris Q Doe
    The central complex of the adult Drosophila brain, required for sensorimotor integration, is transcriptionally complex as detected by single-cell transcriptome analysis.
    1. Developmental Biology
    2. Genetics and Genomics

    The robust, high-throughput, and temporally regulated roxCre and loxCre reporting systems for genetic modifications in vivo

    Mengyang Shi, Jie Li ... Bin Zhou
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Krüppel Regulates Cell Cycle Exit and Limits Adult Neurogenesis of Mushroom Body Neural Progenitors in Drosophila

    Dongni Shao Chen, Jin Man ... Yuu Kimata
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Developmental Biology
    2. Physics of Living Systems

    Spiral-eyes: A soft active matter model of in vivo corneal epithelial cell migration

    Kaja Kostanjevec, Rastko Sknepnek ... Silke Henkes
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in Drosophila melanogaster

    Geovana S Garcia, Murilo F Othonicar ... Marcos T Oliveira
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Cancer Biology
    2. Developmental Biology

    VGLL2 and TEAD1 fusion proteins identified in human sarcoma drive YAP/TAZ-independent tumorigenesis by engaging EP300

    Susu Guo, Xiaodi Hu ... Junhao Mao
    Characterization of recurrent fusion proteins in rhabdomyosarcoma identified a Hippo pathway-independent mechanism involving VGLL2 and TEAD1 driving oncogenic transformation.
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