Bioluminescence imaging in live mice was used to assess the abilities of systemically introduced adeno-associated viral capsids containing enhancer regulatory sequences to target transgene expression to myocardial injuries.
Changes of the chromatin structure suggests how the fate selector transcription factors are activated and how they guide differentiation of GABAergic and glutamatergic neurons in the anterior brainstem.
The hemogenic gastruloid model of embryonic blood development captures multi-wave haematopoiesis and enables interrogation of infant leukaemia cell-of-origin.
Functional organoids prepared from chicken embryonic gut consisting of pacemaker cells and smooth muscles undergo periodic contractions, offering a useful tool to understand rhythm control in multicellular systems.
Disrupting full-length BEND2 impairs ovarian reserve establishment without causing male sterility, highlighting a sex-specific role in fertility and offering new insights into genetic contributions to infertility diagnosis and reproductive health.
A time-course RNA-seq analysis of muscle remodeling reveals transcriptional dynamics independent of autophagy and highlights the significance of BNIP3 in mitochondrial degradation in vivo.
