Browse our latest Developmental Biology articles

Page 18 of 216
    1. Developmental Biology
    2. Genetics and Genomics

    Deficiency in DNAH12 causes male infertility by impairing DNAH1 and DNALI1 recruitment in humans and mice

    Menglei Yang, Hafiz Muhammad Jafar Hussain ... Baolu Shi
    DNAH12 is essential for sperm flagellar development and male fertility in both humans and mice by interacting with dynein proteins DNAH1 and DNALI1.
    1. Developmental Biology

    Opposing roles for Bmp signalling during the development of electrosensory lateral line organs

    Alexander S Campbell, Martin Minařík ... Clare VH Baker
    In sturgeon, fewer electrosensory organs form after targeting Bmp5 for CRISPR/Cas9-mediated mutagenesis, whereas more form after chemically blocking all Bmp signalling shortly before their primordia emerge, suggesting that Bmp signalling has opposing effects during electrosensory organ development.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

    Joshua G Medina-Feliciano, Griselle Valentín-Tirado ... José E Garcia-Arraras
    The intestinal coelomic epithelium provides dedifferentiated precursor cell populations that drive the adult holothurian intestinal regeneration.
    1. Cell Biology
    2. Developmental Biology

    Ovarian Biology: Revisiting the rete ovarii

    Yan Zhang, Hua Zhang
    Long thought to have little relevance to ovarian physiology, the rete ovarii may have a role in follicular dynamics and reproductive health.
    Version of Record
    Insight
    1. Cell Biology
    2. Developmental Biology

    Rediscovering the rete ovarii, a secreting auxiliary structure to the ovary

    Dilara N Anbarci, Jennifer McKey ... Blanche Capel
    The rete ovarii is a complex secretory structure that may play an important role in ovarian homeostasis.
    1. Developmental Biology
    2. Cancer Biology

    Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma

    James Purzner, Alexander S Brown ... Matthew P Scott
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology

    Spatial transcriptomics in the adult Drosophila brain and body

    Jasper Janssens, Pierre Mangeol ... Frank Schnorrer
    Spatial transcriptomics of adult Drosophila brain and body sections determined the spatial expression for 150 genes, which identified the locations of unknown neuronal cell types and transcriptional diversity within muscle.
    1. Developmental Biology

    The autophagy protein ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy

    Pooja Popli, Arin K Oestreich ... Ramakrishna Kommagani
    Autophagy sustains oviduct homeostasis, modulates inflammation, and prevents excessive pyroptosis, ensuring efficient embryo transport and a well-balanced reproductive tract environment.
    1. Cell Biology
    2. Developmental Biology

    Endosomal-lysosomal organellar assembly (ELYSA) structures coordinate lysosomal degradation systems through mammalian oocyte-to-embryo transition

    Yuhkoh Satouh, Takaki Tatebe ... Ken Sato
    Imaging and correlative light and electron microscopy analyses of endosomal-lysosomal organellar assembly in mammalian oocytes elucidated statistic alteration in their size, distribution, and correlation with endo-lysosomal maturation during oocyte-to-embryo transition.
    1. Developmental Biology

    Probing metazoan polyphosphate biology using Drosophila reveals novel and conserved polyP functions

    Sunayana Sarkar, Harsha Sharma ... Manish Jaiswal
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid