Although Oct4 is expressed earlier than Sox2 in mouse embryos, both of them begin to perform their role in activating pluripotency-related genes in the inner cell mass.
Investigation of Aquaporin water channels unveils water inflow and build-up of hydrostatic pressure in endothelial tip cells as a novel mechanism of endothelial cell migration and blood vessel formation.
Ruben Sebastian-Perez, Shoma Nakagawa ... Maria Pia Cosma
The chromatin-bound proteome of embryonic stem cells transitioning to 2C-like cells uncovers chromatin regulators involved in heterochromatin formation.
Volumetric trans-scale imaging with a subcellular resolution across a wide field-of-view of 1.5 × 1.0 cm2 has been realized, facilitating the analysis of cellular dynamics during embryogenesis and brain function.