Browse our latest Developmental Biology articles

Protein nutritional requirements decrease predictively with mass throughout ontogeny across the animal kingdom.

The protein stability of WDR5, the core component of TrxG complex, is controlled by the ubiquitin ligase RNF220, which involves in the maintenance of Hox patterns in mouse hindbrain.

Pkc53E kinase-mediated downregulation of CSL/Su(H) activity is a direct molecular response to parasitoid wasp infestation in Drosophila, allowing the differentiation of encapsulation-active lamellocytes, thereby ensuring an appropriate immune defense.

Modulation of division plane rotation in proliferating chondrocytes determines the ratio of clusters and columns, which may support the multifunctional design of the growth plate.

PTEN mutations disrupt inhibitory GABAergic signaling, causing neurodevelopmental defects that can be mitigated by β-hydroxybutyrate, which activates DAF-16/FOXO and may offer a therapeutic approach for excitation/inhibition imbalances.

Exposure to ketone bodies in early development can reduce neurological impairments in a strain of the nematode C. elegans with PTEN defects.

A single-cell RNA sequencing reveals cell heterogeneity of secondary metabolism in tea plant root and a proposed model in which the theanine biosynthesis pathway occurs via multicellular compartmentation.