Browse our latest Developmental Biology articles

Page 25 of 220
    1. Developmental Biology

    Morphogenesis: Fluid transport comes to the fore

    Yufei Wu, Sean X Sun
    Proteins that allow water to move in and out of cells help shape the development of new blood vessels.
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    1. Developmental Biology

    Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in early mouse embryos

    Yanlin Hou, Zhengwen Nie ... Hans R Scholer
    Although Oct4 is expressed earlier than Sox2 in mouse embryos, both of them begin to perform their role in activating pluripotency-related genes in the inner cell mass.
    1. Developmental Biology
    2. Neuroscience

    Axon Guidance: Watching axons on the move

    Maria I Lazaro-Pena, Carlos A Diaz-Balzac
    The ligand Netrin mediates axon guidance through a combination of haptotaxis over short distances and chemotaxis over longer distances.
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    1. Developmental Biology

    Genetic inactivation of the β1 adrenergic receptor prevents cerebral cavernous malformations in zebrafish

    Wenqing Li, Sara McCurdy ... Mark H Ginsberg
    The β1 adrenergic receptor is a key regulator of cerebral cavernous malformation pathogenesis.
    1. Developmental Biology

    Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis

    Igor Kondrychyn, Liqun He ... Li-Kun Phng
    Investigation of Aquaporin water channels unveils water inflow and build-up of hydrostatic pressure in endothelial tip cells as a novel mechanism of endothelial cell migration and blood vessel formation.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state

    Ruben Sebastian-Perez, Shoma Nakagawa ... Maria Pia Cosma
    The chromatin-bound proteome of embryonic stem cells transitioning to 2C-like cells uncovers chromatin regulators involved in heterochromatin formation.
    1. Developmental Biology

    Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway

    Yunfei Mu, Shijia Hu ... Hongjun Shi
    A ligand independent mechanical sensitive mTORC2-PKC pathway activates Notch in the endocardium of the valve forming area.
    1. Developmental Biology
    2. Neuroscience

    Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo

    Taro Ichimura, Taishi Kakizuka ... Takeharu Nagai
    Volumetric trans-scale imaging with a subcellular resolution across a wide field-of-view of 1.5 × 1.0 cm2 has been realized, facilitating the analysis of cellular dynamics during embryogenesis and brain function.
    1. Developmental Biology
    2. Evolutionary Biology

    Single-cell sequencing provides clues about the developmental genetic basis of evolutionary adaptations in syngnathid fishes

    Hope M Healey, Hayden B Penn ... William A Cresko
    The production of a single-cell atlas for developing syngnathid fish permits study of their unique traits.