Browse our latest Developmental Biology articles

Page 24 of 211
    1. Developmental Biology
    2. Neuroscience

    Adverse impact of female reproductive signaling on age-dependent neurodegeneration after mild head trauma in Drosophila

    Changtian Ye, Ryan Ho ... James Q Zheng
    A head concussion model in fruit flies reveals that early-life exposure to mild concussions significantly increases the risk of late-life neurodegeneration, with females especially vulnerable due to reproductive factors.
    1. Developmental Biology
    2. Genetics and Genomics

    The role of heterochronic gene expression and regulatory architecture in early developmental divergence

    Nathan D Harry, Christina Zakas
    Changes in the amount and timing of gene expression during early development contribute to evolutionary divergence and life-history changes, even within a species.
    1. Cell Biology
    2. Developmental Biology

    H2A.Z deposition at meiotic prophase I underlies homologous recombination and pachytene genome activation during male meiosis

    Shenfei Sun, Yamei Jiang ... Xinhua Lin
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    sisterless A is required for activation of Sex lethal in the Drosophila germline

    Raghav Goyal, Ellen Baxter, Mark Van Doren
    Not revised
    Reviewed Preprint v1
    • Useful
    • Convincing
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    Fertilization: Switching on lysosomes

    Deepak Adhikari, John Carroll
    The formation of large endolysosomal structures in unfertilized eggs ensures that lysosomes remain dormant before fertilization, and then shift into clean-up mode after the egg-to-embryo transition.
    Version of Record
    Insight
    1. Developmental Biology

    FBXO24 deletion causes abnormal accumulation of membraneless electron-dense granules in sperm flagella and male infertility

    Yuki Kaneda, Haruhiko Miyata ... Masahito Ikawa
    FBXO24, a testis-enriched E3 ubiquitin ligase, is essential for sperm flagellum formation and male fertility in mice.
    1. Cell Biology
    2. Developmental Biology

    Caenorhabditis elegans SEL-5/AAK1 regulates cell migration and cell outgrowth independently of its kinase activity

    Filip Knop, Apolena Zounarová ... Marie Macůrková
    The SEL-5/AAK1 kinase unexpectedly influences Wnt signalling-dependent processes in a multicellular organism without using its enzymatic activity.
    1. Developmental Biology
    2. Neuroscience

    Multiple guidance mechanisms control axon growth to generate precise T-shaped bifurcation during dorsal funiculus development in the spinal cord

    Bridget M Curran, Kelsey R Nickerson ... Le Ma
    Formation of dorsal axonal tracts in the spinal cord depends on multiple guidance mechanisms that control growth direction of bifurcating axons in the dorsal root entry zone.
    1. Developmental Biology
    2. Neuroscience

    Semaphorin7A patterns neural circuitry in the lateral line of the zebrafish

    Agnik Dasgupta, Caleb C Reagor ... AJ Hudspeth
    Semaphorin7A sculpts the collective arbor architecture of the lateral line nerve and facilitates neural contacts with the hair cells for synaptogenesis during neuromast development in the zebrafish.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    The transcriptional landscape underlying larval development and metamorphosis in the Malabar grouper (Epinephelus malabaricus)

    Roger Huerlimann, Natacha Roux ... Timothy Ravasi
    Transcriptomic analyses of Malabar grouper show pathways known to be involved in metamorphosis are also upregulated at an early stage of larval development, suggesting an additional function during early development.