Browse our latest Developmental Biology articles

Single-cell transcriptomics enables functional dissection of signaling interactions that drive morphogenesis of complex organ systems.

ECM-Itgb1 signaling and cell-cell adhesion are pivotal and coordinate together to regulate pancreatic islet aggregation, architecture, and functional maturation during development.

The nuclear pore complex is transiently proteolyzed during cell differentiation and the nuclear proteome experience dramatic change.

Organoids are useful in studying guidance cues for retinal ganglion cell (RGC) axon generation and regeneration, and the method of RGC isolation via CNTN2 facilitates investigating RGC-related retinal diseases such as glaucoma.

Pituitary gland size and stem cell number is modulated during early life in the mouse by the imprinted gene Dlk1, which acts in multiple developmental compartments in a dosage-sensitive manner.

The FOXC2⁺ quiescent spermatogonial stem cells are essential for the maintenance of spermatogenesis.

During the evolution of amniotes, the transformation of branchial arches coincided with the drastic remodeling of the ancestral extrinsic cardiac arteries, giving rise to novel ventricular coronary arteries that are unique to amniotes.

Neural plate border cells co-express neural, neural crest, and placodal transcriptional programs before cell fate decisions occur and are transcriptionally heterogeneous along the antero-posterior and medial-lateral axis.

Accumulation of succinate during the in vitro modeling of embryonic stem cell state transition critically regulate cell fate.

Distinct metabolic states coupled with differing morphogen levels regulate HC morphology along the tonotopic axis of the developing chick auditory organ.