Browse our latest Developmental Biology articles

The psychoactive component of cannabis, ∆9-THC, affects cell growth and metabolism in early embryonic cell types in mice.

Dorsoventral gradients of transcription factors NFIA, B, and X impose epigenetic and transcriptional spatial restrictions to olfactory receptor expression.

Mesoderm-derived enteric neurons born in the post-natal vertebrates drive maturation and aging of the enteric nervous system.

Throughout oocyte maturation, there is a simultaneous elevation in the concentrations of Ca²⁺ and Zn²⁺, and the fertilization-induced Ca²⁺ oscillations cease under Zn²⁺-deficient conditions, implying an interplay between these ions, potentially at the IP₃R1 level that harbors a Zn²⁺-binding domain.

The maintenance of proper mitochondrial-associated endoplasmic reticulum membranes is crucial for preventing skeletal muscle atrophy to interact with the Notch signaling pathway.

Although complete mouse in vitro spermatogenesis can be achieved, failure of adult Leydig cell development, with accumulation of progesterone and estradiol, androstenedione deficiency, deregulation of steroidogenic, and steroid target gene expression, were highlighted in organotypic cultures, even with hCG.

Phosphorylation of the pseudokinase Ulk4 by Stk36 promotes primary ciliary tip localization of both proteins to facilitate the phosphorylation and activation of Gli in response to Sonic hedgehog.

Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for members of the Groucho/TCF repressive complex in maintaining non-invasive cell fate in C. elegans.

Imaging experiments reveal the complex and dynamic nature of the transcriptional hubs associated with Notch signaling.