Browse our latest Developmental Biology articles

Dynamic local microenvironments in Drosophila facilitate axonal projection direction transitions in the absence of clear landmarks.

Analyses of transcriptomic dynamics in a new model of human amnion formation identify five continuous amniogenic transcriptional phases as well as a critical role of TFAP2A in amnion fate progression.

Loss of YAP1/TAZ expression in the pancreatic endocrine compartment is not a passive consequence of endocrine specification, rather, Hippo pathway-mediated inhibition of YAP1/TAZ in endocrine progenitors is a prerequisite for endocrine specification and differentiation.

The termination of medulla neuroblasts is specified by the depletion of the neuroepithelium and mediated by apoptosis, differentiation, and gliogenic switch.

Behavioral and circuit analyses show that changes to energetic demand are a key driver of consolidation of daily sleep and feeding patterns as animals mature.

Flow hemodynamic activation of endothelial klf2a is a mechanism regulating initial vascular smooth muscle cell differentiation on circle of Willis arteries.

The transcriptional activation of the key developmental timer gene, microRNA lin-4, is driven by the transmembrane transcription factor MYRF following its temporally regulated self-cleavage at the cell membrane.

Structure-function analysis of the ROR2 cysteine-rich domain reveals a new mechanism of WNT5A reception at the cell surface and provides new insights into the pathogenic mechanisms of Robinow syndrome-driving ROR2 mutations.

PAR-3/Baz function is regulated by CDK1 in asymmetrically dividing cells in the central and peripheral nervous system of Drosophila revealing direct regulation of cell polarity by the cell cycle machinery in the context of cell fate specification.