Browse our latest Developmental Biology articles

Page 59 of 210
    1. Developmental Biology
    2. Evolutionary Biology

    Gene expression phylogenies and ancestral transcriptome reconstruction resolves major transitions in the origins of pregnancy

    Katelyn Mika, Camilla M Whittington ... Vincent J Lynch
    Mammals evolved an invasive placenta early in the origins of pregnancy.
    1. Developmental Biology

    Visceral organ morphogenesis via calcium-patterned muscle constrictions

    Noah P Mitchell, Dillon J Cislo ... Sebastian J Streichan
    Whole-organ live imaging and computational analysis reveal a calcium-mediated mechanical program linking gene expression to organ shape.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons

    Lewis Macdonald, Gillian C Taylor ... Andrew J Wood
    Auxin-inducible degradation of CRISPR-tagged endogenous proteins in mice reveals cell-type-specific dependence on the mitotic chromosome condensation proteins.
    1. Developmental Biology

    Loss of Elp1 disrupts trigeminal ganglion neurodevelopment in a model of familial dysautonomia

    Carrie E Leonard, Jolie Quiros ... Lisa A Taneyhill
    Trigeminal nerve deficits observed in familial dysautonomia, which arises from mutations in ELP1, are due to loss of neural crest-derived TrkA nociceptors, while placode-derived TrkB and TrkC neurons are spared.
    1. Developmental Biology
    2. Genetics and Genomics

    Cre/lox regulated conditional rescue and inactivation with zebrafish UFlip alleles generated by CRISPR-Cas9 targeted integration

    Fang Liu, Sekhar Kambakam ... Maura McGrail
    A novel strategy to create genetic mosaics in zebrafish for cell type-specific analysis of gene function that can be applied to any gene of interest.
    1. Developmental Biology
    2. Genetics and Genomics

    Using population selection and sequencing to characterize natural variation of starvation resistance in Caenorhabditis elegans

    Amy K Webster, Rojin Chitrakar ... L Ryan Baugh
    A powerful sequencing approach is used to elucidate the genetic basis of a complex organismal trait, and members of the irld gene family that affect starvation resistance are identified.
    1. Cell Biology
    2. Developmental Biology

    Morphogenetic forces planar polarize LGN/Pins in the embryonic head during Drosophila gastrulation

    Jaclyn Camuglia, Soline Chanet, Adam C Martin
    Morphogenetic forces from tissue invagination orient cell division through a previously undescribed mechanism of force-dependent LGN/Pins polarization.
    1. Cell Biology
    2. Developmental Biology

    Zebrafish fin regeneration involves generic and regeneration-specific osteoblast injury responses

    Ivonne Sehring, Hossein Falah Mohammadi ... Gilbert Weidinger
    Osteoblast dedifferentiation and migration are injury responses that are differentially regulated and independent of regenerative bone formation.
    1. Developmental Biology

    A dysmorphic mouse model reveals developmental interactions of chondrocranium and dermatocranium

    Susan M Motch Perrine, M Kathleen Pitirri ... Joan T Richtsmeier
    Analysis of 3D reconstructions of chondrocrania of the FgfrcC342Y/+ Crouzon syndrome mouse show the direct effects of this Fgfr2 mutation on embryonic cranial cartilage formation and the indirect effects of chondrocranial morphology on cranial dermal bone development.
    1. Cell Biology
    2. Developmental Biology

    Androglobin, a chimeric mammalian globin, is required for male fertility

    Anna Keppner, Miguel Correia ... David Hoogewijs
    Androglobin, a newly identified mammalian globin with a unique modular structure including a protease and calmodulin binding IQ domain within a circularly permuted globin domain, is implicated in murine spermatogenesis.