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Intercellular communication is critical for organ function, and the role of innervation in mediating this communication is of relevance to many fields, including developmental biology, neuroendocrinology, and disease pathophysiology.

Wings achieve plasticity in size while maintaining robust pattern via ecdysone, which elicits graded responses for growth rates and threshold responses for patterning rates, in the fruit fly Drosophila melanogaster.

The immunoglobulin superfamily cell surface protein Sticks and Stones is a binding partner for the Lar Drosophila receptor tyrosine phosphatase that mediates Lar's developmental functions at the larval neuromuscular junction, mushroom body, and adult optic lobe.

BMP-dependent retinoic acid signaling is responsible for the separation of central from peripheral lineages during neural development.

Actin-related protein 5 antagonizes the interaction of Pbx/Meis with myogenic regulatory factors such as MyoD and MyoG, which is involved in the recruitment of the BRG1-based switch/sucrose nonfermentable chromatin remodeling complex required for myogenic gene activation.

A housekeeping nuclear transport regulator moonlights as a critical determinant of sex-specific regulation of a somatic stem cell niche during the development of Drosophila ovaries.

The hunchback transcription features are compatible with an equilibrium model with a short decay length Bicoid activity gradient as the sole source of positional information, while Zelda and Hunchback speed-up the process by different means.

Loss of the RNA-binding protein TDP-43 impairs the survival of oligodendrocyte progenitors and reactivates growth of mature oligodendrocytes, resulting in inappropriate wrapping of neuronal somata and blood vessels.

Ecdysone-mediated repression of the TMEM16 channel subdued initiates a sensory switch in peripheral nociceptors during Drosophila larval development, increasing thermal nociceptive behavior and reducing responsiveness to ultraviolet light.

Adult mouse fibroblasts maintain an embryonic gene expression signature, inherited from their organ of origin, that is important for organ homeostasis and fibrosis, and may assist in targeting fibrotic diseases in an organ-specific manner.