Browse our latest Developmental Biology articles

Page 69 of 211
    1. Developmental Biology
    2. Evolutionary Biology

    Gene age shapes the transcriptional landscape of sexual morphogenesis in mushroom-forming fungi (Agaricomycetes)

    Zsolt Merényi, Máté Virágh ... László G Nagy
    Allele-specific expression, natural antisense transcripts, and developmental gene expression, but not RNA editing or developmental hourglass, act in concert to shape the transcriptome during the fruiting body formation of complex multicellular fungi.
    1. Developmental Biology

    Hypertrophic chondrocytes serve as a reservoir for marrow-associated skeletal stem and progenitor cells, osteoblasts, and adipocytes during skeletal development

    Jason T Long, Abigail Leinroth ... Matthew J Hilton
    Hypertrophic chondrocytes of the growth plate undergo a process of dedifferentiation to generate marrow associated skeletal stem and progenitor cells (SSPCs), which ultimately re-differentiate into cells of the osteoblast or adipocyte lineages during skeletal development.
    1. Developmental Biology
    2. Neuroscience

    Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain

    Dongjin R Lee, Christopher Rhodes ... Timothy J Petros
    Single-cell sequencing combined with in situ hybridizations reveal dynamic patterns of differentially expressed genes throughout the ventricular and subventricular zone of the embryonic mouse brain, which likely play important roles in cell fate determination.
    1. Developmental Biology
    2. Neuroscience

    Role of Nrp1 in controlling cortical inter-hemispheric circuits

    Fernando Martín-Fernández, Ana Bermejo-Santos ... Marta Nieto
    Transient expression of Nrp1 is required in postnatal stages for terminal arborization and innervation of secondary areas during the development of somatosensory callosal circuits.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants

    Richard J White, Eirinn Mackay ... Elisabeth M Busch-Nentwich
    Allele-specific gene expression can affect the results and interpretation of transcriptomic analyses in zebrafish mutants and has broader implications for work in other outbred organisms.
    1. Developmental Biology
    2. Physics of Living Systems

    Tissue Organization: When cells get in the flow

    Giovanna M Collu, Marek Mlodzik
    New imaging approaches question a long-standing model for how the eyes of fruit flies acquire their geometric patterning.
    Version of Record
    Insight
    1. Cell Biology
    2. Developmental Biology

    Pathway-specific effects of ADSL deficiency on neurodevelopment

    Ilaria Dutto, Julian Gerhards ... Travis H Stracker
    Analysis of adenylosuccinate lyase (ADSL) deficiency in multiple experimental systems reveals cell and organismal phenotypes and impaired neurodevelopment due to the attenuation of ADSL's roles in distinct pathways.
    1. Developmental Biology

    The Cl--channel TMEM16A is involved in the generation of cochlear Ca2+ waves and promotes the refinement of auditory brainstem networks in mice

    Alena Maul, Antje Kathrin Huebner ... Christian A Hübner
    Ano1 deletion disrupts Ca2+ waves within Kölliker’s organ, reduces burst-firing activity and frequency selectivity of auditory brainstem neurons in the medial nucleus of the trapezoid body, and impairs the functional refinement of its projections to the lateral superior olive.
    1. Developmental Biology
    2. Physics of Living Systems

    Emergence of a geometric pattern of cell fates from tissue-scale mechanics in the Drosophila eye

    Kevin D Gallagher, Madhav Mani, Richard W Carthew
    Formation of a triangular lattice of photoreceptor clusters in the compound eye is driven by highly regulated cell flows in the eye epithelium, through a mechanochemical mechanism.
    1. Cell Biology
    2. Developmental Biology

    Somite morphogenesis is required for axial blood vessel formation during zebrafish embryogenesis

    Eric Paulissen, Nicholas J Palmisano ... Benjamin L Martin
    Retinoic acid-dependent somite morphogenesis induces notochord-endoderm separation required for midline angioblast migration and axial blood vessel development.