Browse our latest Developmental Biology articles

Page 94 of 210
    1. Cell Biology
    2. Developmental Biology

    Osmolarity-independent electrical cues guide rapid response to injury in zebrafish epidermis

    Andrew S Kennard, Julie A Theriot
    Skin cells in zebrafish use sodium chloride-dependent electrical gradients to sense tissue injury and guide migration in the appropriate direction to close the wound.
    1. Developmental Biology

    Fgf4 maintains Hes7 levels critical for normal somite segmentation clock function

    Matthew J Anderson, Valentin Magidson ... Mark Lewandoski
    Quantification of fluorescently labeled mRNAs reveals that Fgf4 regulates Notch oscillations in the segmentation clock that controls somitogenesis.
    1. Cell Biology
    2. Developmental Biology

    Rho1 activation recapitulates early gastrulation events in the ventral, but not dorsal, epithelium of Drosophila embryos

    Ashley Rich, Richard G Fehon, Michael Glotzer
    Spatially and temporally patterned activation of the small GTPase Rho1 indicates that ventral-specific factors contribute to cell- and tissue-level behaviors during ventral furrow formation, the first step in Drosophila gastrulation.
    1. Developmental Biology
    2. Evolutionary Biology

    Conservation of peripheral nervous system formation mechanisms in divergent ascidian embryos

    Joshua F Coulcher, Agnès Roure ... Sébastien Darras
    Developmental regulatory mechanisms for peripheral nervous system formation appear to be conserved in ascidians despite extensive genomic divergence after 390 MY of separate evolution.
    1. Cell Biology
    2. Developmental Biology

    Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling

    Yan Xiong, M Julia Scerbo ... Per-Olof Berggren
    Primary cilia on endothelial cells are required for VEGF-A/ VEGFR2-dependent signaling, islet vascularization and, consequently, nutrient delivery and insulin disposal.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Opposing JAK-STAT and Wnt signaling gradients define a stem cell domain by regulating differentiation at two borders

    David Melamed, Daniel Kalderon
    Graded Wnt and JAK-STAT signals regulate the division rate, AP location and differentiation of Drosophila ovarian follicle stem cells to define a domain of stem cells maintained by population asymmetry.
    1. Developmental Biology
    2. Genetics and Genomics

    Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes

    Allen Wang, Joshua Chiou ... NHLBI LungMap Consortium
    Generation of a human lung single nucleus ATAC-seq and single nucleus RNA-seq datasets reveals candidate cis-regulatory elements that advance knowledge on gene expression control in normal and diseased lungs.
    1. Cell Biology
    2. Developmental Biology

    Zebrafish Posterior Lateral Line primordium migration requires interactions between a superficial sheath of motile cells and the skin

    Damian E Dalle Nogare, Naveen Natesh ... Ajay B Chitnis
    Epithelial cells utilize a covering sheath of motile cells to migrate in confinement.
    1. Developmental Biology

    Asymmetric neurogenic commitment of retinal progenitors involves Notch through the endocytic pathway

    Elisa Nerli, Mauricio Rocha-Martins, Caren Norden
    A quantitative live imaging approach unveils that earliest neurogenic progenitors in the vertebrate retina arise from asymmetric divisions and that this asymmetry involves Notch signalling through the endocytic pathway.
    1. Cell Biology
    2. Developmental Biology

    Drosophila hedgehog can act as a morphogen in the absence of regulated Ci processing

    Jamie C Little, Elisa Garcia-Garcia ... Daniel Kalderon
    Hedgehog acts as a morphogen by regulating proteolytic processing and activation of full-length Ci/Gli transcriptional effectors but can pattern Drosophila wing discs normally in the absence of regulated proteolytic processing.