Browse our latest Epidemiology and Global Health articles

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    1. Epidemiology and Global Health

    Healthcare in England was affected by the COVID-19 pandemic across the pancreatic cancer pathway: A cohort study using OpenSAFELY-TPP

    Agnieszka Lemanska, Colm Andrews ... Alex J Walker
    COVID-19 negatively affected pancreatic cancer care by reducing surgical resections and pre-diagnostic testing with BMI and HbA1c, and it also negatively affected the quality of data for research.
    1. Epidemiology and Global Health

    Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults’ primary care records in England through OpenSAFELY

    Louis Fisher, Helen J Curtis ... Ben Goldacre
    There was substantial change in primary care activity following the onset of the COVID-19 pandemic in March 2019 as indicated by key measures reflective of clinical activity in general practice but service was largely restored by April 2021.
    1. Epidemiology and Global Health
    2. Medicine

    Pan-Canadian survey on the impact of the COVID-19 pandemic on cervical cancer screening and management: cross-sectional survey of healthcare professionals

    Mariam El-Zein, Rami Ali ... Survey Study Group
    Decline in cervical cancer screening and challenges faced by healthcare professionals and patients when the pandemic was declared emphasize the importance of implementing human papillomavirus (HPV) primary screening, HPV self-sampling, and telemedicine to continue cervical cancer screening and care.
    1. Epidemiology and Global Health

    Building resilient cervical cancer prevention through gender-neutral HPV vaccination

    Irene Man, Damien Georges ... Iacopo Baussano
    Shifting from girls-only to gender-neutral HPV vaccination strategy improves the resilience of cervical cancer prevention and enhances progress towards cervical cancer elimination.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Association of close-range contact patterns with SARS-CoV-2: a household transmission study

    Jackie Kleynhans, Lorenzo Dall'Amico ... SA-S-HTS Group
    While recognizing study design limitations, the lack of association between household close range proximity events and SARS-CoV-2 transmission, suggests that aerosol transmission may play a larger role than droplet transmission in the household.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    Associations of four biological age markers with child development: A multi-omic analysis in the European HELIX cohort

    Oliver Robinson, ChungHo E Lau ... Martine Vrijheid
    Among European children, shorter telomere length and older DNA methylation age relative to chronological age were associated with poorer behaviors, while older age, as predicted by a novel immunometabolic clock relative to chronological age, was associated with greater cognitive maturity.
    1. Epidemiology and Global Health

    Perceived barriers to cervical cancer screening and motivators for at-home human papillomavirus self-sampling during the COVID-19 pandemic: Results from a telephone survey

    Susan Parker, Ashish A Deshmukh ... Jane R Montealegre
    Mailed at-home HPV self-sampling kits present an opportunity to reduce important barriers to cervical cancer screening among women in a safety net healthcare system.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Integrating contact tracing and whole-genome sequencing to track the elimination of dog-mediated rabies: An observational and genomic study

    Kennedy Lushasi, Kirstyn Brunker ... Katie Hampson
    Contact tracing data reveal how a One Health approach underpinned by dog vaccination interrupts rabies transmission in reservoir populations removing the risk to humans, while virus genome data highlight the importance of surveillance and sustained dog vaccination in connected populations.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    A meta-analysis of genome-wide association studies of childhood wheezing phenotypes identifies ANXA1 as a susceptibility locus for persistent wheezing

    Raquel Granell, John A Curtin ... Adnan Custovic
    Using unique data from five longitudinal UK birth cohorts, four distinct subsets of genetic variants were identified as differentially associated across wheezing phenotypes from infancy to adolescence with little evidence of genetic associations spanning across different phenotypes.
    1. Epidemiology and Global Health
    2. Neuroscience

    Impact of social isolation on grey matter structure and cognitive functions: A population-based longitudinal neuroimaging study

    Laurenz Lammer, Frauke Beyer ... A Veronica Witte
    Analyses of longitudinal neuroimaging data highlight the importance of social contact for brain health.