Browse our latest Evolutionary Biology articles

Page 56 of 113
    1. Evolutionary Biology
    2. Genetics and Genomics

    Cis-regulatory variants affect gene expression dynamics in yeast

    Ching-Hua Shih, Justin Fay
    Allele differences in gene expression dynamics are associated with insertions and deletions and are caused in part by multiple variants within the same promoter region.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    The need for practical insecticide-resistance guidelines to effectively inform mosquito-borne disease control programs

    Alice Namias, Ndey Bassin Jobe ... Silvie Huijben
    With standardized insecticide-resistance assays failing to inform mosquito-control efficacy due to genotype-by-environment effects, practical resistance monitoring under relevant local conditions is needed to correlate resistance, mosquito-control efficacy, and disease epidemiology.
    1. Evolutionary Biology

    The need for high-quality oocyte mitochondria at extreme ploidy dictates mammalian germline development

    Marco Colnaghi, Andrew Pomiankowski, Nick Lane
    Selective transfer of mitochondria in the Balbiani body ensures high-quality oocyte mitochondria at extreme ploidy, explaining many enigmatic features of female germline architecture including germ cell loss.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Highly contiguous assemblies of 101 drosophilid genomes

    Bernard Y Kim, Jeremy R Wang ... Dmitri A Petrov
    One hundred one high-quality drosophilid genomes are released, along with low-cost assembly workflows, as an open community resource for studying genetics, ecology, and evolution in this important model system.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The genomic consequences of hybridization

    Benjamin M Moran, Cheyenne Payne ... Molly Schumer
    A synthesis of recent hybridization literature reveals emerging patterns in the evolution of genomes after hybridization, processes proposed to explain those patterns, and important open questions to direct future hybrid genomics research.
    1. Evolutionary Biology
    2. Physics of Living Systems

    Price equation captures the role of drug interactions and collateral effects in the evolution of multidrug resistance

    Erida Gjini, Kevin B Wood
    A simple mathematical model reveals that antibiotic interactions and collateral effects of evolution are inseparable drivers of multidrug resistance linked by the well-known Price equation from evolutionary theory.
    1. Evolutionary Biology
    2. Structural Biology and Molecular Biophysics

    Structurally distributed surface sites tune allosteric regulation

    James W McCormick, Marielle AX Russo ... Kimberly A Reynolds
    Deep mutational scanning of a synthetic allosteric chimera revealed that a sparse set of mutations on the protein surface improved regulation.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Fast and flexible estimation of effective migration surfaces

    Joseph Marcus, Wooseok Ha ... John Novembre
    Fast and flexible estimation of effective migration surfaces (FEEMS) is a new statistical method that can quickly infer and visualize patterns of migration from genetic data with spatial coordinates.
    1. Ecology
    2. Evolutionary Biology

    Living with relatives offsets the harm caused by pathogens in natural populations

    Hanna M Bensch, Emily A O'Connor, Charlie Kinahan Cornwallis
    Experiments show that pathogens spread more easily among relatives causing increased mortality, but such costs are cancelled out by the benefits of living with kin when pathogens are rare.
    1. Evolutionary Biology
    2. Epidemiology and Global Health
    3. Microbiology and Infectious Disease
    4. Genetics and Genomics

    Evolutionary Medicine: A Special Issue

    Edited by Dominique Soldati-Favre et al.
    eLife is pleased to present a Special Issue to highlight recent advances in the growing and increasingly interdisciplinary field of evolutionary medicine.