Browse our latest Genetics and Genomics articles

The first sequenced mitogenome of a mummified non-human primate connects an Egyptian baboon dated to ca. 800–540 BCE to modern baboon populations in Eritrea, Ethiopia, and eastern Sudan, providing evidence for Egyptian–Adulite trade centuries earlier than current archaeological evidence.

Loss of membrane-bound ICAM-1, overexpression of soluble ICAM-1 or ILKAP activity in tumor cells induce resistance to antigen-specific cytotoxic T-cell-mediated killing independently from regulating antigen presentation, PD-L1 expression, IFN-γ, or TNF-α responsiveness.

A computational approach examines the roles of splicing factors and their association with evolutionary change in splicing.

Germline extrachromosomal circular DNAs are mainly formed by microhomology-mediated ligation of nucleosome-protected fragments and barely contribute to de novo genomic deletions at meiotic recombination hotspots.

The absence of DMRT1 induces a male-to-female sex reversal in XY rabbits and complete infertility in both sexes.

σ²⁸-Dependent sRNAs fine-tune flagella synthesis, with one sRNA connecting synthesis with metabolism and two sRNAs with opposing effects connecting synthesis with ribosomal protein production through unique binding within coding sequences.

A conserved transcriptional signature in macrophages and endothelial cells occurs in multiple organs in response to COVID-19 and suggests potential molecular interactions between the two cell types.

The C. elegans canonical DBL1/TGFβ signaling pathway is not only regulated in response to bacterial challenges, but also appropriately tailors behaviors and molecular immune responses to bacterial challenges, and animals lacking DBL1 respond to specific bacteria as more harmful.

SPOT-MAS (screening for the presence of tumor by methylation and size) is an affordable and effective multi-cancer early detection test analyzing multiple features of circulating tumor DNA.