Browse our latest Genetics and Genomics articles

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    1. Genetics and Genomics

    The genomic landscape of transposable elements in yeast hybrids is shaped by structural variation and genotype-specific modulation of transposition rate

    Mathieu Hénault, Souhir Marsit ... Christian R Landry
    The gain of transposable elements in yeast hybrids does not scale with genetic divergence levels and is most impacted by structural variations and multiple aspects of individual hybrid genetic backgrounds.
    1. Genetics and Genomics
    2. Neuroscience

    Plasticity of gene expression in the nervous system by exposure to environmental odorants that inhibit HDACs

    Sachiko Haga-Yamanaka, Rogelio Nunez-Flores ... Anandasankar Ray
    Volatile compounds from microbes and food alter epigenetic states by inhibiting histone deacetylases and alter gene expression, slow degeneration in Huntington’s model flies, and slow proliferation of a neuroblastoma cell line.
    1. Genetics and Genomics
    2. Neuroscience

    Metabolic and neurobehavioral disturbances induced by purine recycling deficiency in Drosophila

    Céline Petitgas, Laurent Seugnet ... Serge Birman
    1. Genetics and Genomics

    Equity, Diversity and Inclusion: Targeted action to increase inclusion at the Wellcome Sanger Institute

    Saher Ahmed, David J Adams ... Maria Augusta Arruda
    The Sanger Excellence Fellowship has been established to increase the representation of researchers with Black-heritage backgrounds at a leading research centre in the UK.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Epistasis between mutator alleles contributes to germline mutation spectrum variability in laboratory mice

    Thomas A Sasani, Aaron R Quinlan, Kelley Harris
    Germline mutation rates in mice are shaped by two mutator alleles that interact epistatically, showing that DNA repair defects that map to different loci can have snowballing effects.