Browse our latest Genetics and Genomics articles

Page 3 of 141
    1. Genetics and Genomics
    2. Neuroscience

    Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus

    Akanksha Bafna, Gareth Banks ... Patrick M Nolan
    A multiomic study reveals the role of ZFHX3 transcription factor in daily timekeeping with a combination of transcription factor and histone ChIP-seq and time-resolved RNA-seq in the mammalian central clock.
    1. Genetics and Genomics

    MerQuaCo: a computational tool for quality control in image-based spatial transcriptomics

    Naomi Martin, Paul Olsen ... Jack Waters
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Exceptional
    1. Evolutionary Biology
    2. Genetics and Genomics

    The genomic legacy of aurochs hybridisation in ancient and modern Iberian cattle

    Torsten Günther, Jacob Chisausky ... Cristina Valdiosera
    After their introduction to the Iberian peninsula, domestic cattle hybridised with mostly male wild aurochs for millennia until human actions likely ended this process about 4000 years ago.
    1. Cell Biology
    2. Genetics and Genomics

    Cytosolic Carboxypeptidase 5 maintains mammalian ependymal multicilia to ensure proper homeostasis and functions of the brain

    Rubina Dad, Yujuan Wang ... Hui-Yuan Wu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics

    Becker muscular dystrophy mice showed site-specific decay of type IIa fibers with capillary change in skeletal muscle

    Daigo Miyazaki, Mitsuto Sato ... Akinori Nakamura
    BMD mice with three different in-frame deletions corresponded to the severity of BMD patients with the same deletions, and they showed type IIa muscle fibers reduction with morphological capillary changes.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    ZC3H11A mutations cause high myopia by triggering PI3K-AKT and NF-κB mediated signaling pathway in humans and mice

    Chong Chen, Qian Liu ... Xinting Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Evolutionary Biology
    2. Genetics and Genomics

    Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction

    James Boocock, Noah Alexander ... Leonid Kruglyak
    Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating efficiency.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Proteostasis modulates gene dosage evolution in antibiotic-resistant bacteria

    Chinmaya Jena, Saillesh Chinnaraj ... Nishad Matange
    Gene duplication in antibiotic-resistant bacteria mitigates elevated demand for expression, facilitating adaptation to antibiotics and alleviating costs of proteolytic instability of the drug target.
    1. Developmental Biology
    2. Genetics and Genomics

    Evaluating the transcriptional regulators of arterial gene expression via a catalogue of characterized arterial enhancers

    Svanhild Nornes, Susann Bruche ... Sarah De Val
    Identification and characterization of enhancers for eight key arterial genes reveal transcription factors associated with different aspects of endothelial gene expression specificity and provide a tool for a better understanding of arterial differentiation.