Browse our latest Genetics and Genomics articles

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    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Defining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteins

    Roberta Carloni, Tadhg Devlin ... Robin C Allshire
    Synthetic proteins designed to bind specific repetitive DNA sequences in the Trypanosoma brucei genome allow the identification of proteins enriched over different DNA elements.
    1. Developmental Biology
    2. Genetics and Genomics

    Nup107 is a crucial regulator of torso-mediated metamorphic transition in Drosophila melanogaster

    Jyotsna Kawadkar, Pradyumna Ajit Joshi, Ram Kumar Mishra
    Y-complex nucleoporin, Nup107, can regulate ecdysone production by affecting the transcription of Halloween genes and levels of RTK receptor, torso, for the metamorphic transition from larva to pupa.
    1. Genetics and Genomics
    2. Evolutionary Biology

    Faroese Whole Genomes Provide Insight into Ancestry and Recent Selection

    Iman Hamid, Ólavur Mortensen ... Noomi O Gregersen
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Developmental Biology
    2. Genetics and Genomics

    Drosophila melanogaster model of RVCL-S demonstrates age dependent disease progression

    Elena Gracheva, Abigail Matt ... Chao Zhou
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics

    Systematic yeast two-hybrid screening identifies novel functions for SET1C/COMPASS

    Pierre Luciano, Kihyun Park ... Vincent Géli
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Deep mutational scanning reveals pharmacologically relevant insights into TYK2 signaling and disease

    Conor J Howard, Nathan S Abell ... Diane E Dickel
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Developmental Biology
    2. Genetics and Genomics

    Flexible and high-throughput simultaneous profiling of gene expression and chromatin accessibility in single cells

    Volker Soltys, Moritz Peters ... Yingguang Frank Chan
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Constraints on the G1/S transition pathway may favor selection of multicellularity as a passenger phenotype

    Tom Louis Ducrocq, Damien Laporte, Bertrand Daignan-Fornier
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Computational and Systems Biology
    2. Genetics and Genomics

    JAX Animal Behavior System (JABS), a genetics-informed, end-to-end advanced behavioral phenotyping platform for the laboratory mouse

    Anshul Choudhary, Brian Q Geuther ... Vivek Kumar
    The JAX Animal Behavior System integrates standardized hardware, machine learning methods, and annotated datasets to enable reproducible behavioral phenotyping and genetic analysis across diverse mouse strains.
    1. Cell Biology
    2. Genetics and Genomics

    Non-visual light modulates behavioral memory and gene expression in Caenorhabditis elegans

    Zhijian Ji, Bingying Wang ... Dengke K Ma
    Visible light engages a non-visual, bZIP-dependent transcriptional pathway in peripheral tissues that communicates with the nervous system to shape behavioral plasticity and memory, enabling optogenetic-like gene control without photoreceptors.
    Version of Record
    Short Report
    • Important
    • Convincing
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