Browse our latest Immunology and Inflammation articles

The unusually high genetic diversity of MHC genes cannot be explained by heterozygote advantage alone because heterozygote advantage is not expected without some other driver of diversity.

A comprehensive investigation of extracellular asparagine utilization highlights its role as a critical regulator of murine CD4+ T cell activation, differentiation, and function.

Celldetective is an open-source software integrating segmentation, tracking, and event detection to perform high-throughput end-to-end study of dynamic cell interactions, without requiring coding skills, demonstrated on microscopy immunological assays.

Uterine natural killer (NK) cells require TGF-β to be derived from conventional NK cells and contribute to successful pregnancy.

Regulatory immune cells accumulate at the nose-to-brain interface during neuroinflammation, potentially dampening damaging immune responses.

Dissecting protective versus detrimental immune responses uncovers biomarkers and mechanisms that can inform the rational design and evaluation of live attenuated vaccines against African swine fever virus.

Co-culturing pluripotent stem cell-derived hepatocytes and macrophages establishes a physiologically relevant liver model that captures macrophage–hepatocyte interactions, significantly improves hepatocyte maturation, and enables more accurate prediction of immune-mediated drug toxicity.