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    1. Evolutionary Biology
    2. Immunology and Inflammation

    Current insights into insect immune memory

    Gabriela Krejčová, Adam Bajgar
    Insects possess a remarkable ability to develop innate immune memory, and the mechanisms underlying this process are becoming a central topic in innate immunity research.
    1. Immunology and Inflammation
    2. Neuroscience

    Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutières Syndrome neuropathology

    Kelsey M Nemec, Genevieve Uy ... F Chris Bennett
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Exceptional
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Malnutrition drives infection susceptibility and dysregulated myelopoiesis that persists after refeeding intervention

    Alisa Sukhina, Clemence Queriault ... Will Bailis
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    • Incomplete
    1. Immunology and Inflammation

    CD131 contributes to ulcerative colitis pathogenesis by promoting macrophage infiltration

    Zhiyuan Wu, Lindi Liu ... Xiaodong Tan
    CD131 contributes to intestinal inflammation in ulcerative colitis, possibly by promoting the infiltration of macrophages, while targeting CD131 might potentially be a treatment remedy for ulcerative colitis.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Doubling dolutegravir dosage reduces the viral reservoir in ART-treated people with HIV

    Céline Fombellida-Lopez, Aurelija Valaitienė ... Gilles Darcis
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Immunology and Inflammation
    2. Neuroscience

    Glia-mediated gut-brain cytokine signaling couples sleep to intestinal inflammation

    Alina Malita, Anne H Skakkebaek ... Kim Rewitz
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Distinct adaptation and epidemiological success of different genotypes within Salmonella enterica serovar Dublin

    Cheryll M Sia, Rebecca L Ambrose ... Danielle J Ingle
    The most comprehensive analysis of Salmonella Dublin to date uncovers distinct genotypic adaptations, antimicrobial resistance patterns, and virulence strategies that influence epidemiological success.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Tissue-resident memory CD4+ T cells are sustained by site-specific levels of self-renewal and continuous replacement

    Jodie Chandler, M Elise Bullock ... Andrew J Yates
    Memory CD4 T cells within tissues are highly dynamic, and their continuous replacement may erode immunity to previous infections.
    1. Immunology and Inflammation

    Hypothermia protects against ventilator-induced lung injury by limiting IL-1β release and NETs formation

    Nobuyuki Nosaka, Vanessa Borges ... Kenichi Shimada
    Therapeutic hypothermia mitigates ventilator-induced lung injury by suppressing macrophage-derived IL-1β release, thereby reducing neutrophil extracellular trap formation, vascular leakage, and hypoxemia in a two-hit acute lung injury model.
    1. Immunology and Inflammation

    Trained immunity: A new player in cancer immunotherapy

    Shu Li, Yi Zou ... Jun Yan
    Trained immunity is a form of innate immune cell memory that is being developed as a novel immunotherapeutic approach for cancer treatment.
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