Catherine Suzanne Forconi, Christina Nixon ... Ann M Moormann
Pf-GARP antigen seems to be a better malaria vaccine candidate compared to PfSEA-1A, as it triggered the activation of cTFH17, involved in the maintenance of memory antibody responses in adults.
Co-culture between donor-derived iPSC-induced macrophages and forebrain organoids revealed microglial impairment leading to the degenerative neuro-environment in HDLS.
Chemical inhibition or genetic downregulation of glycogen synthase kinase-3 reprograms human monocyte-derived macrophages by enhancing their anti-inflammatory, homeostatic, and reparative functions.
Dendritic cell (DC)-derived IL-27 establishes CD4+ T cell bias against IFN-γ via STAT1 and epigenetics, linking thymic development to autoimmune mechanisms.
Julia M Marchingo, Laura Spinelli ... Doreen A Cantrell
Parallel proteomics and transcriptomics data reveal that PIM kinases have a context-dependent role in promoting mouse CD8 T cell protein translation, effector function, and cell homing.