Browse our latest Immunology and Inflammation articles

Page 2 of 104
    1. Immunology and Inflammation
    2. Cancer Biology

    Androgen deprivation triggers a cytokine signaling switch to induce immune suppression and prostate cancer recurrence

    Kai Sha, Renyuan Zhang ... John J Krolewski
    1. Medicine
    2. Immunology and Inflammation

    NK Cell Exhaustion in Wilson’s Disease Revealed by Single-cell RNA Sequencing Predicts the Prognosis of Cholecystitis

    Yong Jin, Jiayu Xing ... Qingsheng Yu
    1. Immunology and Inflammation

    Uremic toxin indoxyl sulfate induces trained immunity via the AhR-dependent arachidonic acid pathway in end-stage renal disease (ESRD)

    Hee Young Kim, Yeon Jun Kang ... Won-Woo Lee
    Indoxyl sulfate, a key uremic toxin in chronic kidney disease (CKD), induces trained immunity in monocytes via crosstalk between aryl hydrocarbon receptor (AhR)-dependent epigenetic reprogramming by enhancement of the arachidonic acid pathway and AhR-independent metabolic rewiring.
    1. Cancer Biology
    2. Immunology and Inflammation

    DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

    Nicholas J Mullen, Surendra K Shukla ... Pankaj K Singh
    Cancer cell antigen presentation, a requirement for immune-mediated tumor rejection, is induced by dihydroorotate dehydrogenase-inhibitor-mediated cancer cell pyrimidine nucleotide depletion via P-TEFb-dependent transcriptional upregulation of MHC-I and related genes.
    1. Immunology and Inflammation

    LPS-induced systemic inflammation is suppressed by the PDZ motif peptide of ZO-1 via regulation of macrophage M1/M2 polarization

    Hyun-Chae Lee, Sun-Hee Park ... Kyoung Seob Song
    1. Immunology and Inflammation

    Vangl2 suppresses NF-κB signaling and ameliorates sepsis by targeting p65 for NDP52-mediated autophagic degradation

    Jiansen Lu, Jiahuan Zhang ... Xiao Yu
    1. Immunology and Inflammation

    ER-to-lysosome Ca2+ refilling followed by K+ efflux-coupled store-operated Ca2+ entry in inflammasome activation and metabolic inflammation

    Hyereen Kang, Seong Woo Choi ... Myung-Shik Lee
    The role of lysosomal Ca2+ flux associated with K+ efflux, a well-known event in inflammasome activation in metabolic inflammation and inflammasome activation, has been presented.
    1. Medicine
    2. Immunology and Inflammation

    Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns

    Ole Bæk, Tik Muk ... Duc Ninh Nguyen
    1. Immunology and Inflammation

    The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus

    Thomas Morgan Li, Victoria Zyulina ... Theresa T Lu
    Interferon contributes to photosensitivity at least in part by causing Langerhans cell ADAM17 dysfunction, raising the possibility that anifrolumab ameliorates lupus skin disease in part by restoring Langerhans cell function.
    1. Immunology and Inflammation

    Self-inhibiting percolation and viral spreading in epithelial tissue

    Xiaochan Xu, Bjarke Frost Nielsen, Kim Sneppen
    A gene expression data-informed model reveals that a small fraction of interferon-producing cells can effectively constrain early virus spread in epithelial tissue, elucidating connections between critical dynamics and infection heterogeneity.
Newer articles Older articles