Browse our latest Immunology and Inflammation articles

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    1. Cell Biology
    2. Immunology and Inflammation

    Adaptor protein supersaturation drives innate immune signaling and cell fate

    Alejandro Rodriguez Gama, Tayla Miller ... Randal Halfmann
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Immunology and Inflammation
    2. Neuroscience

    Cribriform Plate Microenvironment Assembles a Suppressive Myeloid Network during EAE-induced Neuroinflammation

    Collin Laaker, Martin Hsu ... Zsuzsanna Fabry
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Medicine
    2. Immunology and Inflammation

    A translational transcriptomic signature of vaccine reactogenicity for the evaluation of novel formulations

    Jérémie Becker, Maroussia Roelens ... Laurent Beloeil
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Immunology and Inflammation

    Male-biased Cyp17a2 orchestrates antiviral sexual dimorphism in fish via STING stabilization and viral protein degradation

    Long-Feng Lu, Bao-jie Cui ... Shun Li
    Cyp17a2 enhances antiviral responses in male zebrafish by stabilizing STING through TRIM11-mediated K33-linked polyubiquitination, boosting IFN production.
    1. Immunology and Inflammation
    2. Cancer Biology

    The 1000+ mouse project: large–scale spatiotemporal parametrization and modeling of preclinical cancer immunotherapies

    Adam L Kenet, Sooraj Achar ... Grégoire Altan-Bonnet
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Immunology and Inflammation
    2. Neuroscience

    Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability

    Simone Carneiro-Nascimento, Chao Wei ... Dan Levy
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation

    TGF-β drives the conversion of conventional NK cells into uterine tissue-resident NK cells to support murine pregnancy

    Josselyn D Barahona, Liping Yang ... Wayne M Yokoyama
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Medicine
    2. Immunology and Inflammation

    Endothelial TLR4 signaling drives tissue inflammation, Claudin-5 internalization, and vascular barrier breakdown in a mouse model of neonatal meningitis

    Philip V Seegren, Amir Rattner ... Jeremy Nathans
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation

    Tolerance to Lung Infection in TWIK2 K+ Efflux Mediated Macrophage Trained Immunity

    Josh Thompson, Yufan Li ... Jingsong Xu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Immunology and Inflammation

    An IL-21R hypomorph circumvents functional redundancy to define STAT1 signaling in germinal center responses

    Christoph Jandl, Joanna Warren ... Cecile King
    Not revised
    Reviewed Preprint v1
    • Incomplete
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