The established under-flow migration tracker (UFMTrack) framework allows for automated and scalable studies of immune cell interactions with and extravasation across endothelial monolayer under flow in vitro.
Hella Luksch, Felix Schulze ... Angela Rösen-Wolff
TNF signaling contributes significantly to pathology of constitutively active STING in murine STING-associated vasculopathy with onset in infancy disease.
Gut microbiota composition and sex hormones influence the immune response to methicillin-resistant Staphylococcus aureus gastrointestinal colonization in mice.
Ana Cristina Chang-Gonzalez, Aoi Akitsu ... Wonmuk Hwang
Recognition of antigenic ligand by T-cell receptors is a nuanced process where mechanical force can be leveraged to diversify functional outcomes of different T-cells for the same ligand.
Molecular dynamics simulations reveal that lipid binding at antibody loops and framework regions stabilizes membrane interactions, providing molecular details for neutralization mechanisms and strategies for HIV-1 vaccine development.
