Browse our latest Immunology and Inflammation articles

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    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Deconstructing Complexity: A Computational Topology Approach to Trajectory Inference in the Human Thymus with tviblindi

    Jan Stuchly, David Novak ... Tomas Kalina
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Distinct adaptation and epidemiological success of different genotypes within Salmonella enterica serovar Dublin

    Cheryll M Sia, Rebecca L Ambrose ... Danielle J Ingle
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Compelling
    1. Immunology and Inflammation
    2. Stem Cells and Regenerative Medicine

    IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion

    Daniel L Aldridge, Zachary Lanzar ... Christopher A Hunter
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Immunology and Inflammation
    2. Structural Biology and Molecular Biophysics

    Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry

    Douwe Schulte, Marta Šiborová ... Joost Snijder
    Germline V-gene usage can be inferred from cryoEM reconstructions of antigen-antibody complexes to guide de novo antibody sequencing of complex mixtures by mass spectrometry.
    1. Immunology and Inflammation
    2. Neuroscience

    Photoreceptor loss does not recruit neutrophils despite strong microglial activation

    Derek Power, Justin Elstrott, Jesse Schallek
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Immunology and Inflammation

    MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles

    Linsey Peters, Leonida Rakateli ... Emiel van der Vorst
    Lipid nanoparticles containing microRNA-26-mimics can reduce MASH in mice, providing a novel therapeutic approach.
    1. Immunology and Inflammation

    β-glucan reprograms alveolar macrophages via neutrophil/IFNγ axis to promote lung injury

    Renaud Prével, Erwan Pernet ... Maziar Divangahi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation

    scRNA+TCR-seq Reveals the Proportion and Characteristics of Dual TCR Treg Cells in Mouse Lymphoid and Non-lymphoid Tissues

    Yuanyuan Xu, Qipeng ... Xinsheng Yao
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A modular platform to display multiple hemagglutinin subtypes on a single immunogen

    Dana Thornlow Lamson, Faez Amokrane Nait Mohamed ... Aaron G Schmidt
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Immunology and Inflammation

    UFMTrack, an Under-Flow Migration Tracker enabling analysis of the entire multi-step immune cell extravasation cascade across the blood-brain barrier in microfluidic devices

    Mykhailo Vladymyrov, Luca Marchetti ... Britta Engelhardt
    The established under-flow migration tracker (UFMTrack) framework allows for automated and scalable studies of immune cell interactions with and extravasation across endothelial monolayer under flow in vitro.
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