Browse our latest Immunology and Inflammation articles

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    1. Immunology and Inflammation

    PIM kinase control of CD8 T cell protein synthesis and cell trafficking

    Julia M Marchingo, Laura Spinelli ... Doreen A Cantrell
    Parallel proteomics and transcriptomics data reveal that PIM kinases have a context-dependent role in promoting mouse CD8 T cell protein translation, effector function, and cell homing.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    SARS-CoV-2 nsp16 is regulated by host E3 ubiquitin ligases, UBR5 and MARCHF7

    Li Tian, Zongzheng Zhao ... Zhaolong Li
    E3 ligases UBR5 and MARCHF7 restrict SARS-CoV-2 replications through targeting nsp16.
    1. Immunology and Inflammation

    Diversity and functional specialization of oyster immune cells uncovered by integrative single-cell level investigations

    Sebastien De La Forest Divonne, Juliette Pouzadoux ... Emmanuel Vignal
    Single-cell and functional analyses uncover distinct immune cell types, revealing specialized functions and deepening insight into invertebrate cellular immunity.
    1. Immunology and Inflammation

    Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein

    Kentarou Waki, Hideki Tani ... Nobuyuki Kurosawa
    Analysis of monoclonal immunoglobulin A (IgA) antibodies after intranasal immunization highlights the crucial role of secretory IgA in mucosal immunity, enhancing our understanding of how intranasal vaccines can protect against SARS-CoV-2 infection.
    1. Cell Biology
    2. Immunology and Inflammation

    Monocyte-derived macrophage recruitment mediated by TRPV1 is required for eardrum wound healing

    Yunpei Zhang, Pingting Wang ... Xiaorui Shi
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation

    Interleukin 10 controls the balance between tolerance, pathogen elimination and immunopathology in birds

    Dominique Meunier, Ricardo Corona-Torres ... David A Hume
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Immunology and Inflammation

    Human giant GTPase GVIN1 forms an antimicrobial coatomer around the intracellular bacterial pathogen Burkholderia thailandensis

    Weilun Guo, Shruti S Apte ... Jörn Coers
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Immunology and Inflammation

    RAG suppresses group 2 innate lymphoid cells

    Aaron M Ver Heul, Madison Mack ... Brian S Kim
    Developmental imprinting controls innate type 2 immune function and allergic inflammation.
    1. Immunology and Inflammation

    Bacterial Clearance: With a little help from T cells

    Troy Burtchett, Neal Hammer
    Specific host factors, such as immune cell activity, sex hormones and microbiota composition, influence the ability of Staphylococcus aureus bacteria to colonize the gut of mice.
    Version of Record
    Insight
    1. Immunology and Inflammation
    2. Neuroscience

    Microglia aging in the hippocampus advances through intermediate states that drive activation and cognitive decline

    Jeremy M Shea, Saul A Villeda
    During aging, microglia progress through intermediate cellular states, including stress response and translation upregulation states, that modulate subsequent activation and impact cognitive decline.
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