Browse our latest Immunology and Inflammation articles

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    1. Immunology and Inflammation

    The delayed kinetics of Myddosome formation explains why amyloid-beta aggregates trigger Toll-like receptor 4 less efficiently than lipopolysaccharide

    Bing Li, Prasanna Suresh ... David Klenerman
    Amyloid-beta aggregates and lipopolysaccharide differ in their kinetics of Myddosome formation and size of Myddosome formed, providing an explanation for the less efficient triggering of TLR4 observed with aggregates.
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    PAbFold: Linear Antibody Epitope Prediction using AlphaFold2

    Jacob DeRoo, James S. Terry ... Brian J. Geiss
    1. Immunology and Inflammation

    Secreted antigen A peptidoglycan hydrolase is essential for Enterococcus faecium cell separation and priming of immune checkpoint inhibitor therapy

    Steven Klupt, Kyong Tkhe Fam ... Howard C Hang
    The peptidoglycan hydrolase activity of Enterococcus faecium secreted antigen A is crucial for cell wall remodeling during bacterial cell separation and generates muropeptides that stimulate host immunity to enhance immune checkpoint inhibitor anti-cancer therapy.
    1. Immunology and Inflammation
    2. Cancer Biology

    Unraveling the Power of NAP-CNB’s Machine Learning-enhanced Tumor Neoantigen Prediction

    Almudena Méndez-Pérez, Andrés M. Acosta-Moreno ... Esteban Veiga
    1. Immunology and Inflammation

    G protein subunit Gγ13-mediated signaling pathway is critical to the inflammation resolution and functional recovery of severely injured lungs

    Yi-Hong Li, Yi-Sen Yang ... Liquan Huang
    Conditional abolishment of a G protein subunit in a subset of ectopic tuft cells engenders severer injury, slower recovery, and increased fatality following the infection of the influenza viruses.