Browse our latest Immunology and Inflammation articles

MicroRNA-146b regulates aging, activation, and mitochodrial function in thioglycollate-elicited peritoneal macrophages.

The factors which drive and control disease progression can be inferred from mathematical models that integrate measures of immune responses, data from tissue sampling and markers of infection dynamics.

During pathogen infection, natural killer cells require hypoxia-inducible factor-1α for optimal metabolism to prevent apoptosis, thereby reducing viral load and protecting against morbidity.

Different etiologies of community-acquired pneumonia evoke both shared and diverging immunological responses.

Single-cell RNA-seq analysis reveals an increased complexity of mosquito hemocytes, enabling the functional and molecular characterization of immune cell sub-populations in Anopheles gambiae.

Overlapping action of type I, II, and III interferons maintains microbiome homeostasis, prevents IL-17-driven myeloproliferative disease, and protects against inflammatory bowel disease.

Important nonlinear links between infection, inflammation, and disease severity were revealed using experimentally validated mathematical models.

Rare, virus-specific immune cells in human blood are automatically identified by machine learning algorithm T-REX and characterized for signature features needed for tracking and isolation.

Repertoires of autoreactive murine follicular T helper cells synchronize transiently within one individual.

Upon activation of T cell receptors at the contact site, T cells were substantially stiffened at the cell body as well as at the lamellipodia, which is mediated by Ca²⁺.