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Structural neuroimaging of 40,087 individuals identifies a distinct brain morphological profile associated with metabolic syndrome, linking cardiometabolic risk to cognitive performance, microscale tissue composition, and macroscale brain network architecture.

Gut microbiota-derived gamma-aminobutyric acid is identified as a key metabolite that metformin protect from hepatic ischemia/reperfusion injury.

Open-top Bessel beam two-photon light sheet microscopy have the potential for rapid and accurate nondestructive pathology by visualizing 3D histological information.

The promising potential of plasma extracellular vesicle synaptic proteins as clinical biomarkers of disease progression in Parkinson's disease has been presented.

Exposing new PhD students from underrepresented racial and ethnic groups to the 'hidden curriculum' in graduate school will help prepare them for a career in research.

Corefucosylation contributes to the maintenance of the articular cartilage phenotype and depletion of FUT8 inhibits recovery from cartilage damage and promotes cartilage degeneration.

Ampakines demonstrate efficacy in enhancing bladder function in animal models of spinal cord injury, presenting promising prospects for innovative pharmacotherapy to alleviate post-injury bladder dysfunction.

Genetics, socioeconomic conditions, and family and school environments influence cognitive intelligence in children, and this impact may lead to the individual variability of the current and future PLEs.

PSTPIP2 reduced IL-19 secretion by inhibiting activation of the NF-κB pathway in renal tubular epithelial cells (RTECs), reducing the generation of neutrophil extracellular trap, which can participate in both aristolochic acid I-induced renal injury and apoptosis in RTECs.

A microbiome metabolite alleviates liver steatosis and inflammation, and shows its potential as a therapeutic modality for non-alcoholic fatty liver disease.