Browse our latest Medicine articles

Page 20 of 61
    1. Cell Biology
    2. Medicine

    ErbB signaling is a potential therapeutic target for vascular lesions with fibrous component

    Suvi Jauhiainen, Henna Ilmonen ... Johanna P Laakkonen
    Experimentation on patient biopsies, cell culture, and xenograft models demonstrates involvement of ErbB signaling and fibroblasts in lesion growth, implying that targeting of both stromal and endothelial cells could be a beneficial treatment strategy for patients with venous lesions.
    1. Medicine

    Axonal T3 uptake and transport can trigger thyroid hormone signaling in the brain

    Federico Salas-Lucia, Csaba Fekete ... Antonio C Bianco
    T3 is taken up by axonal termini and is retrogradely transported into endosomal vesicles to the cell nucleus, where it regulates gene expression.
    1. Medicine
    2. Neuroscience

    Instantaneous antidepressant effect of lateral habenula deep brain stimulation in rats studied with functional MRI

    Gen Li, Binshi Bo ... Xiaojie Duan
    Electrical stimulation at the lateral habenula causes an instantaneous remission of depressive symptoms in two rat models, with more medial stimulation sites exhibiting greater antidepressant effects than more lateral stimulation sites, as revealed by functional MRI studies.
    1. Medicine
    2. Neuroscience

    Oxytocin administration enhances pleasantness and neural responses to gentle stroking but not moderate pressure social touch by increasing peripheral concentrations

    Yuanshu Chen, Haochen Zou ... Keith M Kendrick
    A randomized placebo-controlled trial with behavioral, neuroimaging, and physiological measures reveals that oxytocin treatment facilitates pleasure and brain reward responses only to gentle stroking social touch by increasing peripheral blood concentrations.
    1. Biochemistry and Chemical Biology
    2. Medicine

    Improved isolation of extracellular vesicles by removal of both free proteins and lipoproteins

    Dmitry Ter-Ovanesyan, Tal Gilboa ... David R Walt
    A novel immunoassay for ApoB-100, the main protein component of lipoproteins, enables the development of methods to enrich extracellular vesicles from human plasma while depleting both lipoproteins and free proteins.
    1. Medicine
    2. Neuroscience

    Tiered sympathetic control of cardiac function revealed by viral tracing and single cell transcriptome profiling

    Sachin Sharma, Russell Littman ... Olujimi A Ajijola
    Cardiac-specific neurons residing in stellate ganglia comprised of three subsets of neurons based upon their transcriptomic and neurochemical properties and modulates cardiac sympathetic control.
    1. Medicine
    2. Physics of Living Systems

    Comparable in vivo joint kinematics between self-reported stable and unstable knees after TKA can be explained by muscular adaptation strategies: A retrospective observational study

    Longfeng Rao, Nils Horn ... Pascal Schütz
    Muscle synergies are able to identify muscular adaptation that results from feelings of joint instability, whereas tibiofemoral kinematics are sensitive for detecting acute instability events during functional activities.
    1. Medicine

    Biomedical supervisors’ role modeling of open science practices

    Tamarinde L Haven, Susan Abunijela, Nicole Hildebrand
    Supervisors' engagement in open science practices such as data sharing is associated with a greater odds that Ph.D. students engage in these practices and share their data.
    1. Medicine

    Osteoblast-intrinsic defect in glucose metabolism impairs bone formation in type II diabetic male mice

    Fangfang Song, Won Dong Lee ... Fanxin Long
    Osteoblast glucose metabolism is impaired in a mouse model for type II diabetes and can be boosted pharmacologically or genetically to alleviate diabetic osteopenia.
    1. Medicine

    VO2max prediction based on submaximal cardiorespiratory relationships and body composition in male runners and cyclists: a population study

    Szczepan Wiecha, Przemysław Seweryn Kasiak ... Andrzej Klusiewicz
    VO2max in endurance athletes can be accurately predicted by the submaximal cardiopulmonary exercise testing measurements but relying solely on somatic variables allows limited accuracy, which is especially important for physicians and fitness practitioners for proper health and training status monitoring.