Browse our latest Medicine articles

Page 23 of 61
    1. Medicine
    2. Cancer Biology

    International multicenter study comparing COVID-19 in patients with cancer to patients without cancer: Impact of risk factors and treatment modalities on survivorship

    Issam I Raad, Ray Hachem ... Anne-Marie Chaftari
    Remdesivir is a promising treatment modality to reduce 30 day all-cause mortality.
    1. Cancer Biology
    2. Medicine

    Long COVID in cancer patients: preponderance of symptoms in majority of patients over long time period

    Hiba Dagher, Anne-Marie Chaftari ... Issam I Raad
    Long COVID occurred in the majority of cancer patients diagnosed with acute COVID-19 with a preponderance of symptoms (such as fatigue, sleep disturbances, and gastrointestinal symptoms) over a long time period.
    1. Epidemiology and Global Health
    2. Medicine

    Antibody levels following vaccination against SARS-CoV-2: associations with post-vaccination infection and risk factors in two UK longitudinal studies

    Nathan J Cheetham, Milla Kibble ... Claire J Steves
    Third SARS-CoV-2 vaccination appears to eliminate disparities in anti-Spike antibodies between those who received Pfizer-BioNTech versus Oxford/AstraZeneca for first and second vaccination, but levels remain lower in certain groups such as those on the UK 'Shielded Patient List'.
    1. Cell Biology
    2. Medicine

    Efficacy and safety of metabolic interventions for the treatment of severe COVID-19: in vitro, observational, and non-randomized open-label interventional study

    Avner Ehrlich, Konstantinos Ioannidis ... Yaakov Nahmias
    Human metabolism-focused screens reveal clinically promising interventional strategies and repurposing targets to treat COVID-19.
    1. Immunology and Inflammation
    2. Medicine

    Targeted multi-omic analysis of human skin tissue identifies alterations of conventional and unconventional T cells associated with burn injury

    Daniel R Labuz, Giavonni Lewis ... Daniel T Leung
    Compared to non-burn tissue, T cells in burn tissue have a pro-inflammatory rather than a homeostatic tissue-resident phenotype, and unconventional T cells in burn tissue have a higher cytotoxic capacity.
    1. Immunology and Inflammation
    2. Medicine

    FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

    Cong Liu, Milena Schönke ... Patrick CN Rensen
    Fibroblast growth factor 21 blocks hepatic lipid influx and accumulation, prevents Kupffer cell activation, and inhibits the formation of hepatic lipid- and scar-associated macrophages, thereby likely inhibiting fibrogenesis in nonalcoholic steatohepatitis in humanized APOE*3-Leiden.CETP mice.
    1. Epidemiology and Global Health
    2. Medicine

    The impact of lag time to cancer diagnosis and treatment on clinical outcomes prior to the COVID-19 pandemic: A scoping review of systematic reviews and meta-analyses

    Parker Tope, Eliya Farah ... Eduardo L Franco
    Investigating standard lag times prior to the pandemic and identifying key methodological considerations in lag time research can guide future investigations into the impact of time to care for patients with cancer.
    1. Medicine
    2. Neuroscience

    Angelman Syndrome: How late is too late for treatment?

    Lawrence T Reiter
    Experiments on mice suggest that an approach called antisense oligonucleotide therapy may be able to treat some symptoms of Angelman syndrome, including problems with epilepsy and sleep.
    Version of Record
    Insight
    1. Medicine

    Efficacy and safety of endocrine therapy after mastectomy in patients with hormone receptor positive breast ductal carcinoma in situ: Retrospective cohort study

    Nan Niu, Yinan Zhang ... Caigang Liu
    Endocrine therapy after mastectomy may not be recommended for patients with hormone receptor positive ductal carcinoma in situ, even for those with high-risk factors.
    1. Medicine

    Dysregulation of the PRUNE2/PCA3 genetic axis in human prostate cancer: from experimental discovery to validation in two independent patient cohorts

    Richard C Lauer, Marc Barry ... Wadih Arap
    PRUNE2/PCA3 axis dysregulation is an early, rather than late, event in prostate cancer tumorigenesis.