Browse our latest Medicine articles

Page 5 of 62
    1. Immunology and Inflammation
    2. Medicine

    Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns

    Ole Bæk, Tik Muk ... Duc Ninh Nguyen
    Reduced parenteral glucose during neonatal infection redirects hepatic metabolism to oxidative phosphorylation and gluconeogenesis, dampens systemic proinflammatory responses, and significantly enhances survival in preterm newborns.
    1. Medicine
    2. Microbiology and Infectious Disease

    Differences in HIV-1 reservoir size, landscape characteristics, and decay dynamics in acute and chronic treated HIV-1 Clade C infection

    Kavidha Reddy, Guinevere Q Lee ... Thumbi Ndung'u
    Extremely early antiretroviral therapy during HIV-1 subtype C infection leads to faster decline in genome-intact viruses, reduced genetic complexity, and immune escape, and may enhance reservoir clearance with additional interventional strategies.
    1. Cancer Biology
    2. Medicine

    Development and assessment of a sustainable PhD internship program supporting diverse biomedical career outcomes

    Patrick Brandt, Dawayne Whittington ... Rebekah L Layton
    Internship programs for PhD and postdoctoral trainees are challenging to develop and sustain, but the benefits to interns and other stakeholders are significant and worth the effort and expense.
    1. Computational and Systems Biology
    2. Medicine

    Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats

    Hong Yang, Cheng Zhang ... Adil Mardinoglu
    Inhibiting c-Jun N-terminal kinase exerts a cross-tissue therapeutic effect on metabolic dysfunction induced by sucrose overconsumption in rats.
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    R-Spondin Mimetic, SZN-043, Induced Proliferation and Wnt Activity, Two Features Deficient in Human Alcohol-Associated Liver Disease

    Trevor Fisher, Mehaben Patel ... Helene Baribault
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Medicine

    Sperm fertility in mice with oligo-astheno-teratozoospermia restored by in vivo injection and electroporation of naked mRNA

    Charline Vilpreux, Guillaume Martinez ... Jessica Escoffier
    Revised
    Reviewed Preprint v2
    Updated
    • Inadequate
    1. Medicine
    2. Neuroscience

    Cold induces brain region-selective cell activity-dependent lipid metabolism

    Hyeonyoung Min, Yale Y Yang, Yunlei Yang
    It is of significance in identifying temperature sensitive brain regions in brain energy metabolism, as which might provide potential targetable sites in the treatment of brain lipid metabolism-associated neurological disorders.
    1. Medicine

    Special Issue: Reproductive Health

    Edited by Wei Yan et al.
    Our latest Special Issue showcases research in reproductive biology and medicine.
    1. Medicine

    Evaluating Study Design Rigor in Preclinical Cardiovascular Research: A Replication Study

    Isaiah C Jimenez, Gabrielle C Montenegro ... Adrienne Mueller
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Medicine

    A new preprocedural predictive risk model for post-endoscopic retrograde cholangiopancreatography pancreatitis: The SuPER model

    Mitsuru Sugimoto, Tadayuki Takagi ... Hiromasa Ohira
    A PEP risk scoring model that could be calculated before ERCP, SuPER model, may aid in preventing PEP by allowing selection of the appropriate expert endoscopist and useful PEP prophylaxes.