Browse our latest Microbiology and Infectious Disease articles

The anti-HIV drug lenacapavir breaks the HIV capsid by stabilising regions of low curvature at the expense of maintaining a closed shell, leading to loss of viral DNA synthesis and inhibition of infection.

We are writing to respond to comment by Sharma et al, 2024 on our article about the antimalarial drug tafenoquine.

We are writing to comment on the article by Watson et al., 2022 about the antimalarial drug tafenoquine.

Isw1 acts as a master regulator in modulating the expression of drug-resistance genes, and this regulatory mechanism is dependent on the interaction of Isw1 acetylation and ubiquitination.

Real-time visualization of Salmonella enterica and polarized macrophage interaction in the living host identifies an anti-inflammatory, pro-regenerative, and motionless macrophage subset as a survival niche during persistent infection.

Analyses of the stalked budding bacterium Hyphomonas neptunium and its spiral-shaped relative Rhodospirillum rubrum reveal a conserved morphogenetic module that controls the establishment of complex bacterial cell shapes.

Ebola virus VP35 protein evades host antiviral immunity by interacting with STING to sequester IRF3 into inclusion bodies and inhibit type I interferon production.

An enhanced bioinformatic pipeline to quantify Plasmodium falciparum core gene and polymorphic var gene expression revealed changes occurring during early culture adaptation of parasites from naturally infected individuals.

The LOVdeg tag is a versatile tool for bacterial optogenetics, offering modular, blue light-inducible protein degradation for a range of synthetic biology and metabolic engineering applications.

A computational method for predicting evolutionary pathways to antimicrobial resistance, accounting for how epistatic interactions determine trajectories, is described.