A new peptidoglycan hydrolase mined from Acinetobacter baumannii proteome by lysin-derived antimicrobial peptide-primed screening strategy undergoes a unique switch between dimer and monomer after heat treatment and protects mice from A. baumannii infection.
A novel theory demonstrates how variation in the thermal responses of microbial populations can alter coexistance and thus explain patterns of richness across thermal gradients.
Clément Mazeaud, Stefan Pfister ... Laurent Chatel-Chaix
Through interactions with viral RNA and NS5, Zika virus changes the composition of the IGF2BP2-containing ribonucleoprotein complex for the benefit of the viral RNA amplification step of its life cycle.
A combined approach of genome sequencing and fluctuation assays shows that antibiotic pressure does not induce adaptive mutations in Mycobacterium smegmatis, supporting drug resistance as a consequence of phenotypic tolerance.
Bacillus velezensis has broad-spectrum antibacterial activity and can reduce the colonization of Salmonella Typhimurium in the intestinal tract of mice.
Gaetan De Waele, Gerben Menschaert, Willem Waegeman
It is possible to accurately recommend antimicrobial drugs from mass spectra using neural networks and large datasets, paving the way for more efficient clinical diagnostics.
Programmed cell death during plant development (dPCD) is crucial for Arabidopsis thaliana root defense, limiting microbial invasion and maintaining a balanced relationship with beneficial microbes.
The dynamic transcription responses of the human fungal pathogen Candida glabrata during macrophage infection is revealed and a novel transcription factor important for the responses to macrophage, proliferation within macrophage, as well as anti-fungal drug resistance has been discovered.
Certain strains of a bacterium found in the gut of some animals, Lactobacillus plantarum, are able to counter hyperuricemia, a condition caused by high levels of uric acid in the blood.
