Browse our latest Microbiology and Infectious Disease articles

Page 28 of 173
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Benchmarking reveals superiority of deep learning variant callers on bacterial nanopore sequence data

    Michael B Hall, Ryan R Wick ... Lachlan Coin
    Nanopore sequencing effectively resolves key challenges in bacterial small variant detection, providing a more accurate alternative to traditional sequencing methods.
    1. Microbiology and Infectious Disease

    A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides

    Malik Zohaib Ali, Taru S Dutt ... Mercedes Gonzalez Juarrero
    A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides without showing linezolid associated adverse effects.
    1. Microbiology and Infectious Disease

    Interchromosomal segmental duplication drives translocation and loss of P. falciparum histidine-rich protein 3

    Nicholas J Hathaway, Isaac E Kim ... Jeffrey A Bailey
    Sequence analyses show a pfhrp3 deletion mechanism involves duplication of chromosome 11 segment, which is normally removed via negative selection, and specific conditions are needed for spread including low transmission.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Peptidoglycan-Chi3l1 interaction shapes gut microbiota in intestinal mucus layer

    Yan Chen, Ruizhi Yang ... Zhao Shan
    Chi3l1 binds to bacterial peptidoglycan, helping anchor and organize bacteria within the mucus layer.
    1. Microbiology and Infectious Disease

    Cyclic di-GMP as an antitoxin regulates bacterial genome stability and antibiotic persistence in biofilms

    Hebin Liao, Xiaodan Yan ... Yingying Pu
    c-di-GMP and HipH function as a toxin-antitoxin-like module to regulate persister cell formation in bacterial biofilms.
    1. Microbiology and Infectious Disease

    Inhibitors of the small membrane (M) protein viroporin prevent Zika virus infection

    Emma Brown, Gemma Swinscoe ... Stephen Griffin
    A new way to treat Zika virus infections could be achieved following the definition of an ion channel function for the M protein within virus particles.
    1. Microbiology and Infectious Disease

    Peptidoglycan-tethered and free forms of the Braun lipoprotein are in dynamic equilibrium in Escherichia coli

    Yucheng Liang, Jean-Emmanuel Hugonnet ... Michel Arthur
    The Braun lipoprotein is tethered to peptidoglycan independently from the insertion of newly-synthesized peptidoglycan subunits into the expanding cell wall generating a dynamic equilibrium between free and bound protein forms.
    1. Microbiology and Infectious Disease

    A unique cell division protein critical for the assembly of the bacterial divisome

    Xiao Chu, Lidong Wang ... Zhaoqing Luo
    Identifying gain-of-function division variants that suppress the elongated cell division defect phenotype caused by Aeg1 depletion.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    CCL28 modulates neutrophil responses during infection with mucosal pathogens

    Gregory T Walker, Araceli Perez-Lopez ... Manuela Raffatellu
    Chemokine CCL28 plays a key role in shaping neutrophil responses during intestinal Salmonella infection and lung Acinetobacter infection.
    1. Microbiology and Infectious Disease

    A lytic transglycosylase connects bacterial focal adhesion complexes to the peptidoglycan cell wall

    Carlos A Ramirez Carbo, Olalekan G Faromiki, Beiyan Nan
    A lytic transglycosylase connects bacterial focal adhesion complexes to the peptidoglycan cell wall and thus transmits proton motive force from the inner membrane to cell surface.