Browse our latest Microbiology and Infectious Disease articles

Page 26 of 172
    1. Microbiology and Infectious Disease

    Longitudinal transcriptional changes reveal genes from the natural killer cell-mediated cytotoxicity pathway as critical players underlying COVID-19 progression

    Matias A Medina, Francisco Fuentes-Villalobos ... Maria Ines Barria
    Longitudinal transcriptomic analysis of unvaccinated patients reveals that early NK cell cytotoxicity activation distinguishes mild from severe COVID-19, supporting the relevance of concerted innate–adaptive immune responses against the virus.
    1. Microbiology and Infectious Disease

    Intestinal microbiome dysbiosis increases Mycobacteria pulmonary colonization in mice by regulating the Nos2-associated pathways

    MeiQing Han, Xia Wang ... Fan Yang
    Gut microbiota dysbiosis increased Nos2 expression through the 'gut–lung axis', and altered intracellular antimicrobial and anti-inflammatory environment by abnormal NO, ROS, and Defb1, thereby promoting Mycobacteria colonization in mouse lungs.
    Version of Record
    Research Article
    • Important
    • Compelling
    • Incomplete
    1. Microbiology and Infectious Disease

    A Plasmodium falciparum MORC protein complex modulates epigenetic control of gene expression through interaction with heterochromatin

    Maneesh Kumar Singh, Victoria Ann Bonnell ... Celia RS Garcia
    Multi-omic analyses reveal that the chromatin-associated microrchidia protein, MORC (PF3D7_1468100), at the blood stage of the human malaria parasite, Plasmodium falciparum, interacts with a range of nuclear proteins.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Benchmarking reveals superiority of deep learning variant callers on bacterial nanopore sequence data

    Michael B Hall, Ryan R Wick ... Lachlan Coin
    Nanopore sequencing effectively resolves key challenges in bacterial small variant detection, providing a more accurate alternative to traditional sequencing methods.
    1. Microbiology and Infectious Disease

    A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides

    Malik Zohaib Ali, Taru S Dutt ... Mercedes Gonzalez Juarrero
    A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides without showing linezolid associated adverse effects.
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Olfactory basis for essential amino acid perception during foraging in Caenorhabditis elegans

    Ritika Siddiqui, Nikita Mehta ... Varsha Singh
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Peptidoglycan-Chi3l1 interaction shapes gut microbiota in intestinal mucus layer

    Yan Chen, Ruizhi Yang ... Zhao Shan
    Chi3l1 binds to bacterial peptidoglycan, helping anchor and organize bacteria within the mucus layer.
    1. Microbiology and Infectious Disease

    Interchromosomal segmental duplication drives translocation and loss of P. falciparum histidine-rich protein 3

    Nicholas J Hathaway, Isaac E Kim ... Jeffrey A Bailey
    Sequence analyses show a pfhrp3 deletion mechanism involves duplication of chromosome 11 segment, which is normally removed via negative selection, and specific conditions are needed for spread including low transmission.
    1. Microbiology and Infectious Disease

    Cyclic di-GMP as an antitoxin regulates bacterial genome stability and antibiotic persistence in biofilms

    Hebin Liao, Xiaodan Yan ... Yingying Pu
    c-di-GMP and HipH function as a toxin-antitoxin-like module to regulate persister cell formation in bacterial biofilms.
    1. Microbiology and Infectious Disease

    Inhibitors of the small membrane (M) protein viroporin prevent Zika virus infection

    Emma Brown, Gemma Swinscoe ... Stephen Griffin
    A new way to treat Zika virus infections could be achieved following the definition of an ion channel function for the M protein within virus particles.