Microbiology and Infectious Disease

Microbiology and Infectious Disease

eLife publishes research covering virology, bacteriology and mycology. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Microbiology and Infectious Disease

    Toxoplasma TgATG9 is critical for autophagy and long-term persistence in tissue cysts

    David Smith et al.
    ATG9-dependent autophagy is an essential pathway for long-term survival within the cyst in the parasite Toxoplasma gondii and could be exploited in future studies seeking interventions against persistent Toxoplasma infection.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to Toxoplasma gondii

    Joseph T Clark et al.
    Upon Toxoplasma gondii infection, IL-33 plays a critical role in driving early anti-parasite responses by innate lymphoid cells rendered responsive to its effects by infection.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    CRISPR-based functional genomics in human dendritic cells

    Marco Jost et al.
    A CRISPR-based method enables targeted knockouts and genetic screens in human dendritic cells.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Common virulence gene expression in adult first-time infected malaria patients and severe cases

    J Stephan Wichers et al.
    Parasites with pathogenic variant surface antigens are common in adult malaria patients with a naive immune status.
    1. Microbiology and Infectious Disease

    Colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane

    Akshay Sabnis et al.
    Modulation of cytoplasmic lipopolysaccharide levels sensitises bacteria to polymyxin antibiotics, revealing a novel combination therapeutic approach.
    1. Ecology
    2. Microbiology and Infectious Disease

    Multiple lineages of Streptomyces produce antimicrobials within passalid beetle galleries across eastern North America

    Rita de Cassia Pessotti et al.
    The widespread occurrence of metabolically active streptomycetes in Odontotaenius disjunctus beetle frass may insulate their galleries against pathogenic fungal invasion through the production of diverse antimicrobial specialized metabolites.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3

    Francesco Beghini et al.
    The bioBakery 3 platform enables improved, integrated, and strain-level analysis of microbial communities from large-scale meta-omic data.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies

    Christophe Caillat et al.
    The structure of gp41with its membrane anchors highlights the flexible linkage of the transmembrane regions and the fuson peptides, which generates an asymmetric conformation, a potential target of MPER bNAbs.

Senior editors

  1. Miles P Davenport
    University of New South Wales, Australia
  2. Bavesh Kana
    University of the Witwatersrand, South Africa
  3. Päivi Ojala
    University of Helsinki, Finland
  4. See more editors