Browse our latest Neuroscience articles

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    1. Neuroscience

    Emergence of time persistence in a data-driven neural network model

    Sebastien Wolf, Guillaume Le Goc ... Rémi Monasson
    A data-driven model of the neural activity of a circuit essential to swimming orientation in zebrafish can be mathematically interpreted to unveil the dynamical mechanism leading to persistence in tail orientation.
    1. Neuroscience

    Global change in brain state during spontaneous and forced walk in Drosophila is composed of combined activity patterns of different neuron classes

    Sophie Aimon, Karen Y Cheng ... Ilona C Grunwald Kadow
    Major neuron classes are activated when the fly walks, whether it chooses or is forced to do so.
    1. Neuroscience

    Enhanced functional detection of synaptic calcium-permeable AMPA receptors using intracellular NASPM

    Ian Coombs, Cécile Bats ... Mark Farrant
    Intracellular NASPM, unlike the widely used spermine, fully blocks outward currents through calcium-permeable AMPA-type glutamate receptors, enabling an improved functional readout for this physiologically important receptor subtype in neurons.
    1. Neuroscience

    Human endogenous oxytocin and its neural correlates show adaptive responses to social touch based on recent social context

    Linda Handlin, Giovanni Novembre ... India Morrison
    Touch-mediated social interactions in human females elicited endogenous oxytocin and brain responses in a covariant manner, and these changes were modulated by the familiarity of the person delivering touch as well as the recent history of social interaction.
    1. Neuroscience

    Evidence for absence of links between striatal dopamine synthesis capacity and working memory capacity, spontaneous eye-blink rate, and trait impulsivity

    Ruben van den Bosch, Frank H Hezemans ... Roshan Cools
    The absence of generally assumed strong correlations between striatal dopamine synthesis capacity and simple indices of working memory capacity, trait impulsivity, and spontaneous eye-blink rate warrants caution for using these traits as proxy measures to replace direct striatal dopamine assessments.
    1. Neuroscience

    Spike-phase coupling patterns reveal laminar identity in primate cortex

    Zachary W Davis, Nicholas M Dotson ... John H Reynolds
    By examining the relationship between spike timing and the phase of the LFP across cortical layers, researchers can use a stereotyped phase-coupling pattern as a diagnostic marker for electrode depth when other methods of electrode placement are ambiguous.
    1. Neuroscience

    Ventral striatum dopamine release encodes unique properties of visual stimuli in mice

    L Sofia Gonzalez, Austen A Fisher ... J Elliott Robinson
    Dopamine release in the nucleus accumbens in mice encodes the rate and magnitude of rapid environmental luminance changes rather than visual stimulus novelty or threat intensity.
    1. Neuroscience

    Elucidating a locus coeruleus-dentate gyrus dopamine pathway for operant reinforcement

    Elijah A Petter, Isabella P Fallon ... Henry H Yin
    Mice can learn to press a lever persistently for activation of a dopaminergic projection from the locus coeruleus to the hippocampal dentate gyrus.
    1. Neuroscience

    A genetic variant of fatty acid amide hydrolase (FAAH) exacerbates hormone-mediated orexigenic feeding in mice

    Georgia Balsevich, Gavin N Petrie ... Matthew N Hill
    A genetic knock-in mouse model reveals that the endocrine state governs the effect of the common fatty acid amide hydrolase C385A variant on body weight through a hypothalamic-mediated mechanism.
    1. Medicine
    2. Neuroscience

    The need to change: Is there a critical role of midlife adaptation in mental health later in life?

    Friederike Thams, Stefanie Brassen
    A new developmental model of cognitive-emotional adaptation in midlife builds on current findings from lifespan psychology, cognitive neuroscience, and research in late-life depression.