Browse our latest Neuroscience articles

Page 222 of 599
    1. Neuroscience

    Cerebellum encodes and influences the initiation, performance, and termination of discontinuous movements in mice

    Michael A Gaffield, Britton A Sauerbrei, Jason M Christie
    The activity of cerebellar Purkinje cells both represents and participates in organizing the temporal structure of a periodically performed motor action.
    1. Neuroscience

    Flexible utilization of spatial- and motor-based codes for the storage of visuo-spatial information

    Margaret M Henderson, Rosanne L Rademaker, John T Serences
    When human participants are able to plan responses in a visuo-spatial working memory task, sensory-like representations of remembered spatial position in early visual and parietal cortex adaptively trade off with motor-like representations of upcoming actions in sensorimotor cortex.
    1. Cell Biology
    2. Neuroscience

    Microtubule assembly by tau impairs endocytosis and neurotransmission via dynamin sequestration in Alzheimer’s disease synapse model

    Tetsuya Hori, Kohgaku Eguchi ... Tomoyuki Takahashi
    Wild-type human recombinant tau protein infused in presynaptic terminals newly assembled microtubules, which sequestered cytosolic dynamins, thereby blocking synaptic vesicle endocytosis and causing activity-dependent rundown of excitatory synaptic transmission in a slice model of mouse brainstem.
    1. Neuroscience

    Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence

    Sarah Rose Anderson, Jacqueline M Roberts ... Monica L Vetter
    In postnatal retina, neuronal apoptosis promotes a spectrum of microglial transcriptional states with varied dependence on CSF1R; TAM receptor Mer and complement receptor 3 mediate phagocytosis of dying neurons while altered CSF1R dependence requires Axl.
    1. Neuroscience

    A-type FHFs mediate resurgent currents through TTX-resistant voltage-gated sodium channels

    Yucheng Xiao, Jonathan W Theile ... Theodore R Cummins
    A-type fibroblast growth factor homologous factors generate resurgent currents in tetrodotoxin-resistant voltage-gated sodium channels, increase repetitive firing of sensory neurons, and provide a potentially important target for pain treatment strategies.
    1. Medicine
    2. Neuroscience

    Cold protection allows local cryotherapy in a clinical-relevant model of traumatic optic neuropathy

    Yikui Zhang, Mengyun Li ... Wencan Wu
    Local deep hypothermia combined with hibernation-mimicking cold protection is neuroprotective in a translatable large animal model of traumatic optic neuropathy.
    1. Neuroscience

    Drosophila TRPγ is required in neuroendocrine cells for post-ingestive food selection

    Subash Dhakal, Qiuting Ren ... Youngseok Lee
    Genetic, behavioral, and biochemical evidence reveals that the Drosophila TRPγ channel is required in neuroendocrine cells for the starvation-induced switch in preference to less palatable but more nutritive food.
    1. Cell Biology
    2. Neuroscience

    Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors

    Soo Jeong Kim, Youngsik Woo ... Sang Ki Park
    Rai14-Tara complex enhances the stability of dendritic spines and synaptic connections relevant to depressive-like behaviors.
    1. Neuroscience

    Competition between parallel sensorimotor learning systems

    Scott T Albert, Jihoon Jang ... Reza Shadmehr
    When a common error drives parallel implicit and explicit learning systems, increases in the explicit response will suppress implicit adaptation.
    1. Computational and Systems Biology
    2. Neuroscience

    Early lock-in of structured and specialised information flows during neural development

    David P Shorten, Viola Priesemann ... Joseph T Lizier
    In developing neural cell cultures, information flows lock-in early and nodes undertake specialised computational roles.