Ross D Markello, Aurina Arnatkeviciute ... Bratislav Misic
The abagen toolbox provides researchers with tools to systematically process and analyze imaging transcriptomics data, improving standardization of workflows and enabling more comprehensive evaluation of research findings.
Circuit-wide calcium imaging during C. elegans foraging elucidates the functional architecture of a neural circuit controlling the choice between two alternative behavioral states.
Davide Cavalieri, Alexandra Angelova ... Rosa Cossart
Embryonic birthdate is a crucial determinant of heterogeneity among CA1 principal neurons, which include a previously overlooked subpopulation of pioneer neurons.
Activity levels in anterior and posterior cholinergic basal forebrain neurons are associated with distinct aspects of global brain state, sensory salience, reward expectation, and aversive reinforcement learning.
Rawan AlSubaie, Ryan WS Wee ... Andrew F MacAskill
Amygdala input to ventral hippocampus is both excitatory and inhibitory, and the balance of these two projections controls the formation of place preference via differential innervation of each hippocampal output population.
Interactions between near but distinct (<1 mm) structures such as cortical layers in the rodent brain can be studied by a new micro-optical tool that is low-cost and capable of multilayer optical recordings, optogenetic stimulations, or both.
Haleigh N Mulholland, Bettina Hein ... Gordon B Smith
In vivo calcium imaging reveals that prior to visual experience, inhibitory spontaneous activity in the developing visual cortex is highly modular and participates in large-scale correlated networks that are co-aligned to excitatory activity.