Browse our latest Neuroscience articles

Page 319 of 642
    1. Neuroscience

    In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system

    Lori Glenwinkel, Seth R Taylor ... Oliver Hobert
    Neuron type-specific gene batteries share cis-regulatory motifs.
    1. Neuroscience

    The Prop1-like homeobox gene unc-42 specifies the identity of synaptically connected neurons

    Emily G Berghoff, Lori Glenwinkel ... Oliver Hobert
    Circuit transcription factors may define the differentiation and assembly of distinct neurons into functional circuitry.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model

    Frédéric Frottin, Manuela Pérez-Berlanga ... Mark S Hipp
    Protein aggregates resulting from mutations in C9orf72 impair different aspects of cellular quality control in the cytosol and the nucleus, but mRNA-mediated effects contribute more strongly to toxicity.
    1. Neuroscience

    Uncovering a ‘sensitive window’ of multisensory and motor neuroplasticity in the cerebrum and cerebellum of male and female starlings

    Jasmien Orije, Emilie Cardon ... Annemie Van der Linden
    Despite the structural sexual dimorphism in the song control system, both male and female starlings experience similar seasonal neuroplasticity in multisensory systems and cerebellum during the photosensitive phase, which acts as a sensitive window of plasticity.
    1. Neuroscience

    Cortical signatures of precision grip force control in children, adolescents, and adults

    Mikkel Malling Beck, Meaghan Elizabeth Spedden ... Jesper Lundbye-Jensen
    Precise motor control is supported by connectivity within a cortical grasping network from childhood to adulthood, but older individuals display more top-down control and superior motor performance compared to children.
    1. Neuroscience

    Dorsal raphe nucleus to anterior cingulate cortex 5-HTergic neural circuit modulates consolation and sociability

    Laifu Li, Li-Zi Zhang ... Fa-Dao Tai
    Inhibition of 5-HT neurons in the dorsal raphe nuclei or 5-HT terminals in the anterior cingulate cortex decreased consolation-like behaviors and reduced sociability.
    1. Computational and Systems Biology
    2. Neuroscience

    Low-dimensional learned feature spaces quantify individual and group differences in vocal repertoires

    Jack Goffinet, Samuel Brudner ... John Pearson
    Modern machine learning methods offer new techniques for analyzing complex vocal behavior like ultrasonic mouse calls and birdsong.
    1. Neuroscience

    ß-arrestin 2 germline knockout does not attenuate opioid respiratory depression

    Iris Bachmutsky, Xin Paul Wei ... Kevin Yackle
    The key mechanism for opioid-like biased agonists to provide analgesia but not respiratory depression does not involve ß-arrestin 2.
    1. Cell Biology
    2. Neuroscience

    High-fidelity, efficient, and reversible labeling of endogenous proteins using CRISPR-based designer exon insertion

    Haining Zhong, Cesar C Ceballos ... Tianyi Mao
    A high-fidelity and efficient strategy to use CRISPR/Cas9 to reversibly insert large DNA fragments into somatic cells to label or modify endogenous proteins for research and, in the future, for gene therapy.
    1. Neuroscience

    Spatially displaced excitation contributes to the encoding of interrupted motion by a retinal direction-selective circuit

    Jennifer Ding, Albert Chen ... Wei Wei
    The direction-selective circuit in the retina adjusts the contributions of excitatory and inhibitory mechanisms under different stimulus conditions to generate context-dependent neural representations of visual features.