Alexa Pichet Binette, Guillaume Theaud ... PREVENT-AD Research Group
White matter microstructure alterations in key bundles affected in Alzheimer's disease are related to amyloid and tau pathology in the preclinical phase of sporadic and autosomal-dominant Alzheimer's disease.
Michael Bucher, Stephan Niebling ... Marina Mikhaylova
Autism-associated SHANK3 missense mutations result in differential protein folding, stability, and intramolecular dynamics affecting its turnover at the synapse.
Teresa M Findley, David G Wyrick ... Matthew C Smear
To track odors borne on turbulent airflow, mice strategically follow their nose, with sampling movements and sensory computations reminiscent of those demonstrated in nematodes and insects.
Songbirds can use arbitrary visual cues to immediately, flexibly and adaptively control syntax of learned song vocalizations in a manner that parallels human cognitive control over syllable sequencing in speech.
Briana J Martiszus, Timur Tsintsadze ... Stephen M Smith
External calcium regulates neuronal excitability via its actions on voltage-gated sodium channels but not by regulating NALCN via the calcium-sensing receptor.
Cognitive reconstitution after pharmacologic unconsciousness is an extended process, executive function is more robust than expected, and the healthy human brain is resilient to the effects of deep general anesthesia.
Marta Maltese, Jeffrey R March ... Nicolas X Tritsch
In addition to modulating firing rates, the neurotransmitter dopamine exerts a strong influence on the overall number of neurons in striatum that are recruited during behavior.