Dopaminergic medication has differential effects on the discovered electrophysiological networks, which could be used to develop new electrical and pharmacological interventions in Parkinson’s disease.
Unbiased and targeted genetic approaches reveal a link between sleep and autophagy that could be relevant for sleep function, and for understanding pathological consequences of chronic sleep loss.
Philip Jean-Richard-dit-Bressel, Jessica C Lee ... Gavan P McNally
Punishment insensitive individuals are not more impulsive or anxious, they dislike aversive outcomes and predictors of these outcomes, but are simply less likely to learn their control over them.
Vijay K Samineni, Jose G Grajales-Reyes ... Robert W Gereau
Circuit and transcriptional analysis shows that genetically defined central amygdala neurons and their projections to the ventral periaqueductal gray mediate behavioral and affective responses to pruritus.
Benoit P Delhaye, Ewa Jarocka ... Philippe Lefèvre
Synchronous recording of skin deformations at the contact with a transparent surface and of tactile afferents from the fingertip reveals that afferents signal incipient slip.
Colin M Cleary, Brenda M Milla ... Daniel K Mulkey
Cellular and chemogenetic approaches identify a novel mode of chemotransduction involving regulation of basal breathing by CO2/H+-dependent disinhibition.
Elizabeth B Brown, Kreesha D Shah ... Alex C Keene
The taste system of fruit flies is activated by broad classes of fatty acids and can discriminate between different classes, revealing previously underappreciated complexity in the coding of tastants.