Hippocampal and prefrontal neuronal populations form slow behavioral-timescale (~seconds) and fast cognitive-timescale (~100 ms) sequential activity patterns as theta and replay sequences, which play distinct yet cooperative roles in memory-guided decision-making.
J Roman Arguello, Liliane Abuin ... Richard Benton
Targeted expression of molecular probes for gene expression and chromatin accessibility in subpopulations of neurons in the Drosophila olfactory system identifies genes required for their development and function.
Sina C Rosenkranz, Artem A Shaposhnykov ... Manuel A Friese
Inducing neuronal mitochondrial activity during central nervous system inflammation counteracts inflammation-induced neuronal electron transport chain deficiency and calcium toxicity, thereby protecting against neuronal loss in a multiple sclerosis mouse model.
Gregory G Grecco, Briana E Mork ... Brady K Atwood
A novel, translational mouse model of prenatal methadone exposure was developed and a longitudinal assessment of offspring revealed impairments in physical, behavioral, and neuronal development.
Hannah C Goldbach, Bradley Akitake ... Mark H Histed
In a simple visual task, that in principle could be performed using information in V1 alone, perturbations of secondary visual areas impair perception.
Model-based fMRI reveals the neurocomputational bases of accepting a bribe when power-holders consider two moral costs, conniving with a fraudulent briber and the harm brought to a third party.
Two-photon in vivo calcium imaging reveals short time-scale, synchronous and sparse population activity in dentate gyrus that replays place-related information, and is important for formation of dentate-dependent spatial memory.
Oligodendrocytes with an enhanced ability to withstand cytotoxic stress display an increased capacity to remyelinate demyelination lesions of the CNS in the presence of an inflammatory environment.
Timely regulation of growth cone dynamics, including filopodial and cytoskeletal rearrangements through phosphorylation signals from glial cells, shapes the photoreceptor axon targeting.
Jamie L Courtland, Tyler WA Bradshaw ... Scott H Soderling
Cellular etiology of a human WASH complex mutation in mice reveals its specific roles in neuronal organelle trafficking and a surprising role in motor impairments.
