Browse our latest Neuroscience articles

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    1. Computational and Systems Biology
    2. Neuroscience

    Bayesian inference for biophysical neuron models enables stimulus optimization for retinal neuroprosthetics

    Jonathan Oesterle, Christian Behrens ... Philipp Berens
    Bayesian simulator-based inference is used to infer the parameters of complex multicompartment models of retinal neurons from two-photon imaging data.
    1. Neuroscience

    Emergence of non-canonical parvalbumin-containing interneurons in hippocampus of a murine model of type I lissencephaly

    Tyler G Ekins, Vivek Mahadevan ... Chris J McBain
    An excess of novel non-canonical subtypes of parvalbumin+ interneurons in a mouse model of classical lissencephaly, which possess non-fast-spiking physiological properties, may contribute to network hyperexcitability common in this model.
    1. Neuroscience

    Gamma activity accelerates during prefrontal development

    Sebastian H Bitzenhofer, Jastyn A Pöpplau, Ileana Hanganu-Opatz
    Maturation of inhibitory feedback accelerates gamma activity in the medial prefrontal cortex during development.
    1. Developmental Biology
    2. Neuroscience

    Leptin suppresses development of GLP-1 inputs to the paraventricular nucleus of the hypothalamus

    Jessica E Biddinger, Roman M Lazarenko ... Richard Simerly
    Leptin acts cell autonomously on brainstem neurons that express GLP-1 to suppress development of excitatory viscerosensory inputs to the hypothalamus.
    1. Neuroscience

    Convergence of cortical types and functional motifs in the human mesiotemporal lobe

    Casey Paquola, Oualid Benkarim ... Boris C Bernhardt
    A novel model of the human mesiotemporal lobe suggests that its broad roles in cognition can be explained by how its cytoarchitecture and form relate to large-scale functional motifs.
    1. Neuroscience

    Alcohol potentiates a pheromone signal in flies

    Annie Park, Tracy Tran ... Nigel S Atkinson
    For Drosophila melanogaster, the scent of alcohol—normally associated with preferred egg-laying sites—potentiates a male pheromone signal, thereby increasing the aggressive competition between males for the reproductive resource.
    1. Neuroscience

    A low affinity cis-regulatory BMP response element restricts target gene activation to subsets of Drosophila neurons

    Anthony JE Berndt, Katerina M Othonos ... Douglas W Allan
    DNA motifs tuned for low affinity binding of BMP-induced pMad/Medea transcription factors function to restrict gene activation to small subsets of the many Drosophila neurons that exhibit active BMP signaling.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis

    Markus Terrey, Scott I Adamson ... Susan L Ackerman
    The translational GTPase GTPBP1 prevents ribosome stalling during tRNA deficiency and is necessary for neuronal survival.
    1. Neuroscience

    Natural ITD statistics predict human auditory spatial perception

    Rodrigo Pavão, Elyse S Sussman ... José L Peña
    Human brain has incorporated natural statistics of spatial cues to the neural code supporting perception of sound location.
    1. Cell Biology
    2. Neuroscience

    Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A

    Antonietta Franco, Xiawei Dang ... Gerald W Dorn II
    A trial of mitofusin activation shows neuron regeneration and phenotype reversal in vitro and in vivo in experimental Charcot–Marie–Tooth disease type 2A caused by mitofusin 2 mutations.