Browse our latest Neuroscience articles

Vps29 promotes retromer localization in the adult Drosophila brain, engaging Rab7 and TBC1D5, and its loss triggers age-dependent neuronal impairments in endolysosomal trafficking and synaptic transmission.

In mouse brain slices, native delta glutamate receptors carry ionic current and underlie the α1-adrenergic receptor-mediated depolarization of dorsal raphe neurons that drives action potential firing in vivo.

Cross-species alignment based on cortical myelin content can dissociate cortical expansion and relocation from changes in connectivity profiles in the temporal lobe of higher primates.

Neuronal networks with strong functional specificity of connections between excitatory and inhibitory neurons show specific dynamics of inhibitory stabilization, accompanied with rapid spontaneous activity transitions between highly selective functional states.

Simulations predict a paradoxical effect that should be revealed by patterned stimulation of the cortex.

Orthogonal to traditional paradigms that manipulate neuroligin expression level, optogenetic stimulation of tyrosine phosphorylation highlights a role of the intracellular domain of endogenous neuroligin-1 in excitatory synaptic differentiation and potentiation.

Direct and indirect pathways in the basal ganglia have opposing effects not only on action performance but also on internal timing of expected reward delivery.

The nucleotide sensing ability of IMPDH1 at the Bateman domain is regulated by light-dependent phosphorylation in the retina, to adjust GTP synthesis to illumination conditions.

Elucidating the contribution of augmented artificial skin-stretch stimulation to the fingertips to the immediate illusion of a higher stiffness and to an increased predictive grip force control.

Cognitive performance is supported by symbiotic metabolic and neuro-vascular responses in task-specific brain networks.