Browse our latest Neuroscience articles

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    1. Neuroscience

    Temporal chunking as a mechanism for unsupervised learning of task-sets

    Flora Bouchacourt, Stefano Palminteri ... Srdjan Ostojic
    Model-based analyses of human behaviour and neural activity show that representations of concurrent task-sets emerge by merging together representations of individual stimulus-response associations that occur in temporal proximity.
    1. Neuroscience

    Categorical representation from sound and sight in the ventral occipito-temporal cortex of sighted and blind

    Stefania Mattioni, Mohamed Rezk ... Olivier Collignon
    The categorical organization of the ventral occipito-temporal cortex, typically thought to be a visual region, is actually partially independent of visual input and even visual experience.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    The Cryo-EM structure of pannexin 1 reveals unique motifs for ion selection and inhibition

    Kevin Michalski, Johanna L Syrjanen ... Toshimitsu Kawate
    The structure of a pannexin 1 uncovers the extracellular loops of pannexin 1 as important structural motifs for ion selectivity and channel inhibition.
    1. Neuroscience

    Visually-updated hand state estimates modulate the proprioceptive reflex independently of motor task requirements

    Sho Ito, Hiroaki Gomi
    Distortion and elimination of limb visual feedback affects low-level stretch reflex control, indicating the involvement of a high-level and multimodal representation of the limb state in orchestrating hierarchical sensorimotor control.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Ion Channels: Taking a close look at a large-pore channel

    Pablo S Gaete, Jorge E Contreras
    The structure of pannexin 1, a channel protein with a large pore, has been determined for the first time.
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    Insight
    1. Developmental Biology
    2. Neuroscience

    Extracellular matrix-inducing Sox9 promotes both basal progenitor proliferation and gliogenesis in developing neocortex

    Ayse Güven, Nereo Kalebic ... Wieland B Huttner
    Transcription factor Sox9 has an important role in neocortex expansion, where its expression in basal progenitors increases proliferation, induces premature gliogenesis and promotes the expression of extracellular matrix components.
    1. Cell Biology
    2. Neuroscience

    The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction

    Ana Rita Costa, Sara C Sousa ... Monica M Sousa
    The axonal cytoskeletal contains an actomyosin-II network that controls circumferential axonal contraction and expansion with the potential of regulating fluctuations in diameter during action potential firing, trafficking, and degeneration.
    1. Neuroscience

    Prediction signals in the cerebellum: Beyond supervised motor learning

    Court Hull
    Emerging evidence suggests a broad role for cerebellar circuits in generating and testing predictions about movement, reward, and diverse cognitive processes.
    1. Neuroscience

    Movement-related coupling of human subthalamic nucleus spikes to cortical gamma

    Petra Fischer, Witold J Lipski ... R Mark Richardson
    When coupling between STN spikes and cortical gamma oscillations was strong, subsequent movement was initiated earlier, independent of changes in mean firing rates, demonstrating the importance of relative spike timing.
    1. Neuroscience

    Spatiotemporal patterns of neocortical activity around hippocampal sharp-wave ripples

    J Karimi Abadchi, Mojtaba Nazari-Ahangarkolaee ... Majid H Mohajerani
    The hippocampus and neocortex engage in waves of mutual excitation wherein a sharp wave-ripple may occur at any time before, during or after the peak of the hippocampal-neocortical activation.