Judit García-González, Alistair J Brock ... Caroline H Brennan
Zebrafish studies are able to predict loci and biological pathways affecting human behaviour, paving the way to better understanding of the biological underpinnings of psychiatric disease.
The ability to smoothly perceive the environment across saccades without disturbing retinal motion sensations is generated by eye movement contingent habituation.
Zora Chui-Kuen Chan, Hiu-Lam Rachel Kwan ... Chi Wai Lee
Postsynaptic MT1-MMP serves as a molecular switch to synaptogenesis by clearing the surrounding ECM environment that allows effective deposition of nerve-derived synaptogenic factors to induce postsynaptic differentiation at developing NMJs.
Cue cells in the medial entorhinal cortex encode visual cues during virtual navigation, supporting the hypothesis that the brain represents visual cue information to error-correct grid cell firing during path-integration.
Roger Shen Zhang, Kif Liakath-Ali, Thomas C Südhof
Knockout of both latrophilin-2 and latrophilin-3 from Purkinje cells in mice selectively impairs parallel-fiber synapses, revealing a redundant but critical function for latrophilins at specific synapses.
Julie Hamaide, Kristina Lukacova ... Annemie Van der Linden
Song learning accuracy can be predicted and traced in the structural properties of the brains of juvenile male zebra finches already at 20 days post-hatching.
Everyday soundscapes dynamically engage attention towards target sounds or salient ambient events, with both attentional forms engaging the same fronto-parietal network but in a push-pull competition for limited neural resources.
Matthew P McCabe, Erin R Cullen ... Matthew C Weston
The crucial regulator of brain function, mTOR, signals through distinct macromolecular complexes to control how synaptic vesicles are released from the presynaptic terminal.