Pyramidal cells of the subiculum, a major output cell type of the hippocampus, can be deconstructed into distinct subtypes that exhibit a patchwork-like organization in space.
Nathaniel J Miska, Leonidas MA Richter ... Gina G Turrigiano
Sensory deprivation suppresses cortical responsiveness through a selective remodeling of excitatory and inhibitory microcircuit motifs, by simultaneously amplifying feedforward and suppressing feedback excitation.
The learning rate for novel spatial environments in model networks of place cells is determined by the product of the window for plasticity and the auto-correlation of place-cell activity.
Elizabeth Nicholson, Dmitry A Kuzmin ... Dimitri Michael Kullmann
Neurons can synchronize, supporting flexible communication among brain areas; closed-loop optogenetics allows the frequency and power of population oscillations to be dissociated, providing a tool to interrogate how networks couple.
Signals from primate rod photoreceptors do not exhibit the light-level-dependent routing through parallel retinal circuits observed in rodents and often invoked in interpreting psychophysical experiments.
Speeded value-based decisions between two options can be affected by a third, high-value distractor that captures attention and slows down the choice process.
Heun Soh, Suhyeorn Park ... Anastasios V Tzingounis
Loss of potassium channel activity from fast-spiking interneurons increases their excitability leading to unexpectedly increased fast excitatory transmission and seizure susceptibility.
