The BB model explains spatial cognition in terms of interactions between specific neuronal populations, providing a common computational framework for the human neuropsychological and in vivo animal electrophysiological literatures.
Michael A Gaffield, Matthew J M Rowan ... Jason M Christie
In behaving mice, inhibition from molecular layer interneurons attenuates excitation of Purkinje cells by parallel fibers and suppresses their ability to enhance climbing fiber-triggered dendritic Ca2+ responses.
PlexB plays a multifaceted role in instructing the assembly of the Drosophila olfactory circuit through temporally-regulated expression patterns and expression level-dependent effects.
Osama F Harraz, Thomas A Longden ... Mark T Nelson
TRPV4 channels in brain capillaries are suppressed by the phosphoinositide PIP2 and activated by receptor agonists implicated in neurovascular coupling.
Michael Troup, Melvyn HW Yap ... Bruno van Swinderen
Optogenetic activation reveals a larger role for the fly brain 'sleep switch' neurons in controlling both waking and sleeping behavioral responsiveness, partly via a parallel channel involving innexin6 electrical synapses.
The first non-invasive technique to assess the action of brain clearance mechanisms, driven by the perivascular inflow of cerebrospinal fluid, has been developed using magnetic resonance imaging.
Conditional deletion of the DYT1 dystonia protein torsinA causes selective cell autonomous neurodegeneration of striatal and brainstem cholinergic neurons, and severe motor behavioral abnormalities.
Ludivine Pidoux, Pascale Le Blanc ... Arthur Leblois
The cerebellum sends a functional input to the song-related basal ganglia via the thalamus in songbirds that can modify premotor activity, and it participates to song learning in juvenile birds.
Antonio H Lara, Gamaleldin F Elsayed ... Mark M Churchland
Voluntary movements are preceded by a temporally flexible preparatory neural process that is present regardless of whether movement is initiated rapidly or thoughtfully.
