A hub in the rostral anterior cingulate cortex receives unusually high and functionally diverse inputs, providing a biological interface between motivation, incentive based learning, and decision making.
Calcium imaging is used to construct a model of Caenorhabditis elegans nervous system dynamics capable of predicting future behavioral switches on a trial by trial basis and across individual animals.
Striatal dopamine 2/3 receptor (D2/3R) availability is related to working memory-induced functional connectivity changes in the default mode network, and this mediates the relationship between D2/3Rs and task performance.
Joshua S Talboom, Asta Håberg ... Matthew J Huentelman
An internet-based cohort study of paired associate learning shows that a first-degree family history of dementia is associated with lowered performance, an effect modified by apolipoprotein E genotype and diabetes.
Maternally experienced environmental stress leads to multigenerational inheritance of ethanol preference and an altered rewards pathway in Drosophila melanogaster.
Christina Chatzi, Yingyu Zhang ... Gary L Westbrook
Single episodes of voluntary exercise induced a functional increase in hippocampal synapses mediated by activity-dependent expression of the BAR protein Mtss1L, acting as a novel early effector of synapse formation.
In multi-channel sensory systems, gain adaptation can help maintain not only coding capacity across changes in signal intensity, but also combinatorial representations of odor identity.